Research Specialist, Temporary Position (3-months)
The Harvey Cushing Neuro-oncology Laboratory in the Department of Neurosurgery is seeking a research specialist to perform translational studies on brain tumors. The project will involve analysis of patient gene expression data with the goal of identifying tractable targets for therapy. The scientist must have expertise in standard molecular and cell biological techniques. Must be hard-working and a team player, with a PhD in a related discipline. This is a grant funded, three-month, temporary position only.
The objectives of this study are to evaluate the transcriptional profile of 770 genes associated with immuno-oncology and tumor microenvironment (Pan-Cancer Immune-Profiling Panel - NanoString) in 100 glioblastoma (GBM) samples and correlate with patient's response to TMZ treatment, survival, clinical and molecular characteristics of the tumors (such as MGMT methylation and IDH mutations). The results of this study may contribute to understanding the GBM immunological microenvironment, identification of new biomarkers and development of new drugs and therapeutic compounds involved in immuno-oncology.
Ph.D. preferred. MS degree or equivalent education and experience in molecular and cell biological techniques, with a focus in neuro-oncology. Candidate must possess:
Strong research design and analytical skills.
Strong database statistical skills.
In-depth knowledge of field of research.
Excellent time management/organizational skills.
Strong written and verbal presentation skills.
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