Temp Senior Scientist I, Protein Engineering

Headquarters Location: South San Francisco, CA

Candidate Location: Hybrid

Travel Required: 5%

Reports To: VP, Protein Engineering, Bioinformatics & Computational Biology

Department: Protein Engineering

Position Type: Temporary (12 months), Non-Exempt

About CytomX Therapeutics:

CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engaging bispecific antibodies ("TCBs"), and immune modulators such as cytokines and checkpoint inhibitors ("CPIs"). Learn more at www.cytomX.com.

Who You Are and What You'll Do:

You are passionate about life sciences and making a difference to cancer patients, their families, and healthcare providers. You will be responsible for leading design and engineering efforts to generate novel PROBODY protein therapeutics and supporting their development. You will help develop a team to creatively build and expand CytomX's platform and core technologies. The successful candidate will work as a TEMP for up to 12 months in the Structural Biology team and lead projects to elucidate structures of PROBODY proteins.

Job Responsibilities:

• Represent Protein Engineering function on project teams (internal and partnered) and lead engineering efforts to design and optimize PROBODY protein therapeutic candidates derived from antibodies, bispecific proteins, and cytokines

• Creatively lead development and expansion of CytomX platform technology in the conditionally-activated therapeutic space

• Champion structural projects in the Structural Biology team

• Mentor 1-2 research associates

Minimum Qualifications:

• Ph.D. and at least four years of industry experience in antibody/protein engineering

Preferred Qualifications:

• Must have a solid command of current DNA cloning and molecular biology techniques (qPCR, RT-PCR)

• Must have hands-on X-ray crystallography experience; experience in NMR, EM, or cryoEM is desirable

• Must have experience in developing and using ELISAs to study molecular interactions

• Experience with FACS, bacterial/phage library screening, and next-generation sequence methods is highly desired

How You Will Work:

• Demonstrates collaboration and teamwork. Works well with others and understands that collaboration leads to better results.

• Possesses strong communication skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.

• Exhibits strong interpersonal skills and self-awareness. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.

• Shows continuous improvement and a commitment to self-management and development. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.

• Demonstrates a patient focus. Puts the patient first in actions and decisions taken.

• Demonstrates ability and commitment to building effective teams. Attracts, develops, and retains diverse top talent. Aligns, mobilizes, and engages others to achieve and sustain peak performance.

• Has a track record of driving vision and purpose in teams.

Compensation and So Much More

• The expected salary range for this role based on the primary location for this position in California starts at $77.00 per hour. Offer amounts are determined by factors such as experience, qualifications, geographic location, and other job-related factors permitted by law.
• A great environment where we work collaboratively, leverage each other's strengths, and work toward a shared vision with our common goals of doing the best thing for patients.

Conditions of Employment

• Background investigations are required for all positions at CytomX, consistent with applicable law.

CytomX's Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)

CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.

Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at hr@cytomx.com

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at hr@cytomx.com

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