Cytomx Therapeutics South San Francisco , CA 94080
Posted 7 days ago
Headquarters Location: South San Francisco, CA
Candidate Location: Hybrid
Travel Required: 5%
Reports To: Sr. Scientist I, Protein Sciences & Early CMC
Department: Protein Sciences
Position Type: Temporary (6 months), Non-Exempt
About CytomX Therapeutics:
CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engaging bispecific antibodies ("TCBs"), and immune modulators such as cytokines and checkpoint inhibitors ("CPIs"). Learn more at www.cytomX.com.
Who You Are and What You'll Do:
You are passionate about life sciences and making a difference to cancer patients, their families, and healthcare providers. You will participate in the expression and purification of protein reagents to support all discovery and development programs at CytomX. The successful candidate will work as a TEMP for up to 6 months in the Protein Sciences department.
Job Responsibilities:
Conduct QC testing of DNAs that goes into transfection.
Support the protein production by small- and large-scale transient transfection of CHO/293 cells.
Develop strategies to improve the protein expression process for PROBODY Therapeutics, bispecific molecules, and cytokines.
Support the small-scale purification of PROBODY Therapeutics, bispecific molecules, and cytokines.
Express PROBODY Therapeutics, various bispecific molecules, and cytokines with fed batch cultures.
Minimum Qualifications:
BS in Biochemistry or related discipline with 6+ years of experience in the biotechnology or MS in Biochemistry with 4+ years of experience in the biotechnology or biopharma industry.
Hands-on experience with mammalian cell cultures and aseptic techniques is required.
Prior experience in transient transfection process of CHO/293 cells is required.
Experience with Vi-CELL and OCTET is required.
Experience in protein characterization assays such as concentration, endotoxin measurement, SDS-PAGE and SEC-HPLC is required.
Preferred Qualifications:
Experience in protein purification using Tecan liquid handler system and AKTA systems is preferred.
Experience in antibodies and other protein purification techniques is preferred.
How You Will Work:
Demonstrates collaboration and teamwork. Works well with others and understands that collaboration leads to better results.
Possesses strong communication skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.
Exhibits strong interpersonal skills and self-awareness. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.
Shows continuous improvement and a commitment to self-management and development. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.
Demonstrates a patient focus. Puts the patient first in actions and decisions taken.
Compensation, Benefits, and So Much More
Conditions of Employment
CytomX's Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)
CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.
Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at hr@cytomx.com
Notice to Recruiters/Staffing Agencies
Recruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at hr@cytomx.com
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Cytomx Therapeutics