Staff Research Associate

Position Summary

Located at the UCLA California NanoSystems Institute (CNSI), the Molecular Screening Shared Resource (MSSR) combines the intellectual prowess of the top-ranked U.S. public university with the industrial infrastructure, rigor and nimbleness of pharmaceutical research operations. With 120 publications over the last 20 years leading to multiple compounds in clinical trials, the MSSR has a superb track record of drug discovery in academia.

The broad impact of our work has led to clinical candidates in disease indications including cancer as well as neurological and infectious diseases. The first compound stemming from research at the MSSR (TRE-515) is now in clinical trial Phase I and we have many more projects in the pipeline. Our approach takes full advantage of our ability to integrate robotics, small molecule libraries, the latest developments in genome engineering and functional genomics to find new cures and solve humanity's most pressing challenges.

The MSSR's industry grade resources include over 300,000 compounds and arrayed genome-wide functional genomics libraries that cover all modalities (CRISPR, shRNA, cDNA and siRNA).Under the supervision of the MSSR Director, the Staff Research Associate plays a role in generating novel cell line models for our research using functional genomics tools. Additional responsibilities include working on assays and high throughput screening campaigns, supporting the academic community through mentoring of graduate students and postdocs, improving workflows and efficiencies and providing hands-on technical expertise/scientific guidance as well as mentoring members of the academic community.

Salary & Compensation

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Qualifications

Early-stage professional experience; training will be provided on state-of-the-art automation and next generation technologies. (Preferred) Skilled at FACS, molecular biology, mammalian cell culture and assay development. Previous experience with both nonviral- and virus-based gene delivery approaches. (Required) Proven ability to think outside of the box and be mentally flexible. Ability to handle multiple projects simultaneously and meet project timelines. Ability to integrate and collaborate within a high-achieving team environment. Skill in prioritizing assignments to complete work in a timely manner wit (Required) Previous work experience in a cross-functional team. (Preferred) Exceptional verbal communication and scientific writing skills. (Required) Demonstrated knowledge of biological, chemical and radiation safety rules, and ability to keep lab in compliance with the regulations. Demonstrated skill with tissue culture procedures including cell line generation. Demonstrated skill in performing chemical and mathematical calculations. (Required) Demonstrated skill in operating a binocular phase microscope, personal computer, spectrophotometer, tissue culture equipment, autoclave, and balance. (Required) Ability to train and assess work done by subordinates/other laboratory personnel. Ability to establish and maintain cooperative working conditions and relationships with other staff members and students. (Required) Ability to learn about high throughput machinery and apply knowledge to projects. Skill in use of standard computer software and ability to learn necessary other software platforms. (Required) Skill in molecular biology procedures such as DNA preparations, lentiviral packaging and infection of cells with virally packaged constructs. - preferred (Preferred) Ability to organize ordering information, lab protocols, lab stock inventories of viruses, cells, and bacterial stocks. Demonstrated ability to manage large compound collections, conserve the quality of the collections and monitor and document compound consumption. Ability to maintain an organized l (Required) Ability to communicate and perform well in deadline situations and maintaining a steady workflow. Skill in working independently and following through on assignments. Work well on multiple projects at the same time. (Multitasking). (Required) Ability to work on a flexible schedule, including evenings and weekends. (Required)

Education, Licenses, Certifications & Personal Affiliations

Bachelor's Degree BS Degree in Microbiology, Cell Biology, Biochemistry, Molecular Bio. or related field & min. of 3 years of relevant lab experience, preferable industrial exp. or equivalent combo of education & exp (Required)

Special Conditions for Employment

Background Check: Continued employment is contingent upon the completion of a satisfactory background investigation.

Schedule

8:00am to 5:00pm

Union/Policy Covered

RX-Research Support Professionals

Complete Position Description

https://universityofcalifornia.marketpayjobs.com/ShowJob.aspx?EntityID=38&JDName=Staff%20Research%20Associate%202%20(PASIREQ_363)