Staff Research Associate, Tech Dev

Guardant Health, Inc. Redwood City , CA 94063

Posted 2 months ago

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform is designed to leverage our capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs.

In pursuit of our goal to manage cancer across all stages of the disease, Guardant Health has launched two liquid biopsy-based tests, Guardant360 and GuardantOMNI, for advanced stage cancer patients, and is developing programs for recurrence and early detection, called Project LUNAR. Since its launch in 2014, Guardant360 has been used by more than 5,000 oncologists, over 40 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers.

Position Summary:

To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Staff Research Associate to help develop, test, and improve sample preparation technologies for rare variant studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.

As a Research Associate supporting product and technology development, you will work with members within the team and interface with multiple teams including process engineering, clinical operations, research operations, and bioinformatics. You will be hands on in the lab and be required to design, implement, and validate new technologies related to liquid biopsy sequencing assays for the early detection, treatment, and monitoring of all cancer types.

Essential Duties and Responsibilities:

  • Operate next generation sequencing instruments

  • Run sequencing sample preparation assays in medium to high throughput environment

  • Test and improve new sequencing sample preparation assays

  • Log and track research samples throughout sequencing workflow

  • Maintain appropriate inventory of lab supplies

  • Bring a can do attitude to solve new and challenging problems in a high pace environment

  • Analyze data and troubleshoot issues within the tech dev team and among other teams

  • Collaborate with all functions within project teams

  • Engage in early design of products and perform experiments both independently and under the supervision of Senior team members.

  • Be able to present updates, write reports and SOPs, and contribute to technical discussions

  • 8-12 years related experience

  • The ability to handle biological samples (i.e. tissue, biofluid, etc) is a must

  • Excellent written and oral communication skills is a must

  • Professional hands-on experience in industrial setting in genomics field

  • Hands-on experience in running sequencing platforms and assays is a plus

  • Experience with process automation for nucleic acid extraction and sample preparation is a plus

  • Education: BSc, MSc or Ph.D. in Molecular Biology, Genetics, Biochemistry or related field

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.


icon no score

See how you match
to the job

Find your dream job anywhere
with the LiveCareer app.
Mobile App Icon
Download the
LiveCareer app and find
your dream job anywhere
App Store Icon Google Play Icon
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Clinical Research Associate

Guardant Health, Inc.

Posted 3 weeks ago

VIEW JOBS 3/28/2019 12:00:00 AM 2019-06-26T00:00 Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. Its Guardant Health Oncology Platform is designed to leverage its capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs. In pursuit of its goal to manage cancer across all stages of the disease, Guardant Health has launched multiple liquid biopsy-based tests, Guardant360 and GuardantOMNI, for advanced stage cancer patients, which fuel its LUNAR development programs for recurrence and early detection. Since its launch in 2014, Guardant360 has been used by more than 6,000 oncologists, over 50 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers. Position Summary: The Clinical Research Associate (CRA) for the LUNAR program is responsible for management and monitoring activities that will lead to successful execution of clinical studies. They will proactively identify and resolve clinical project issues and participate in process improvement initiatives as applicable. The CRA engages with study investigators, vendors and internal/external stakeholders as a member of the Clinical Trial Operations team. Essential Duties and Responsibilities: * Responsible for all aspects of study site monitoring including routine monitoring and close-out of clinical sites, maintenance of study files, conduct of pre-study and initiation visits. * Involvement in the generation of project plans, especially those related to site management, monitoring and reporting. * Involved in the development of protocols and Case Report Forms (CRFs) as assigned. * Manage the identification, selection and feasibility processes. * Ensure the study staff who will conduct the protocol have received the proper materials and instructions to safely enter patients into the study. * Ensure the protection of study patients by verifying that informed consent procedures and protocol requirements are adhered to according to the applicable regulatory requirements. * Ensure the integrity of the data submitted on Case Report Forms (CRFs) or other data collection tools by careful source document review and monitor for missing or implausible data. * Prepare accurate and timely trip reports. * Organize and make presentations at Investigator Meetings. * Interact with internal groups to evaluate needs, resources and timelines. * Act as contact for clinical trial supplies and other suppliers (vendors) as assigned * University/college degree (life science preferred), or certification in a related allied health profession from an appropriately accredited institution, nursing, medical or laboratory technology * Minimum of two (2) years of clinical research monitoring experience (including pre-study, initiation, routine monitoring and closeout visits) at a Pharmaceutical, Biotech or CRO company. Diagnostic and/or Medical device experience preferred. * Oncology experience preferred * Thorough knowledge of ICH/GCP Guidelines, including a basic understanding of regulatory requirements in other countries * Advanced site monitoring skills * The ability to thrive with minimal supervision * The drive to resolve project-related problems and can prioritize workload for self and team * Efficient and effective work habits in a matrix environment, internally and externally. * A flexible attitude to adjust to changing needs * The ability and willingness to travel up to 70% of the time. * Excellent knowledge of MS Office as well as project management and clinical trials software. Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time. Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. All your information will be kept confidential according to EEO guidelines. Please visit our career page at: http://www.guardanthealth.com/jobs/ Guardant Health, Inc. Redwood City CA

Staff Research Associate, Tech Dev

Guardant Health, Inc.