Senior Scientist/Associate Principal Scientist - Formulation And Analytical Method Development

Job Description:

We are seeking a highly experienced Senior Scientist/Associate Principal Scientist - Formulation and Analytical Method Development to be a part of our rapidly growing talented research and development teams. This person will help advance our drug development platform with a strong background in nanoparticle drug delivery systems.

Responsibilities:(including, but not limited to):

• Responsible for conceiving and delivering nanoparticle formulations to support early discovery and preclinical studies.

• Conduct experiments, independently and in collaboration with colleagues in support of project goals.

• Characterize polymers, drug substance and nanoparticles using advanced analytical and characterization techniques (HPLC, DLS, NMR, etc.)

• Perform formulation characterization using techniques such as pH, osmolality, particle sizing, and zeta potential

• Identifying potential stability and performance issues with prototype formulation

• Develop cutting-edge conjugation chemistries to further advance Aviceda's proprietary glyco-immunology platform.

• Collaborate and integrate with chemistry/biology workflow to develop and screen nanoparticles with desired properties.

• Develop/sustain relationships with CROs to conduct animal studies and be the point person for material supply.

• Additional responsibilities include formulation/analytical support for CMC activities such as drug product manufacturing, evaluating batch records and regulatory filings.

• Maintain general laboratory functionality, including lab equipment maintenance and lab supplies.

• Drive Aviceda's innovation with novel ideas and detailed documentation

Requirements:

• Minimum of M.S. with 3 to 5+ years or Ph.D. with 2 to 5 years of related experience in the biotech industry. Degree in Pharmaceutical sciences, Materials Science, Polymer Chemistry, Chemical Engineering, Chemistry, or a related field.

• Background in nanoparticle formulation development strongly desired. Specific background in polymeric nanoparticles is a strong plus.

• Prior experience working on sterile dosage form would be a plus.

• Hands-on experience in development of processes such as micro-fluidization, evaporation, TFF and sterile filtration.

• Prior experience on HPLC method development will be plus.

• Strong communication, organizational and interpersonal skills are necessary for this role

• Demonstrated record of working successfully with cross-functional teams including early research and development and CMC teams.

• Ability to work in a fast-paced environment with a sense of urgency and handle multiple roles.

• Work in close collaboration within the research team to ensure successful completion of projects. Ability to plan and manage complex activities and prioritize tasks to deliver on

Education:

• M.S./Ph.D. in Pharmaceutical sciences, Materials Science, Polymer Chemistry, Chemical Engineering, Chemistry, or a related field.