Senior Scientist, Stem Cell Biology

Intrexon San Diego , CA 92140

Posted 3 months ago

Description:

DUTIES AND RESPONSIBILITIES:

  • Lead a high-performance technical and support team on reproductive biology projects. Responsible for derivation and maintenance of primary cells, adult stem cells, and pluripotent stem cells (ESC/iPSCs) for various therapeutic programs.

  • Responsible for process development of primary cells, adult stem cells, and pluripotent stem cells.

  • Execute high throughput screens to assess functionality and differentiation ability of stem cells and gene-modified stem cells.

  • Actively collaborate with other CEU teams, other intrexon divisions and external research and commercial partners as applicable to support technology transfer and collaborative projects.

  • Maintain expert knowledge of current literature.

  • Propose continual process improvements for efficiency and quality.

  • Prepare technical reports and make clear and succinct scientific presentations that can be shared and transferred to and from cross-functional teams.

  • Perform other duties as assigned.

MANAGEMENT RESPONSIBILITIES:

Supervise 1-3 employees

  • Provide leadership, drive change, and execute on the company's mission and core values.

  • Cross-train and coach staff to maintain an efficient, lean, and knowledgeable team.

  • Coordinate and lead regular project meetings.

  • Create a weekly and daily schedule for the team; coordinate individual and teamwork assignments that foster innovation and produce results.

  • Create SMART (specific, measurable, attainable, relevant, and time-bound) metrics for the team to follow and monitor their advancement on projects under rapidly shifting priorities and timelines.

  • Ensure relevant safety protocols and instructions are readily available and strictly adhered to.

EDUCATION AND EXPERIENCE:

  • Ph.D. in stem Cell Biology, developmental biology, reproductive biology, Molecular Biology, or related field.

  • Minimum 5-10 years' experience, industry experience preferred.

  • Extensive expertise in pluripotent stem cell culture, in particular adult stem cells, ES cells, iPS cells.

  • Characterization, maintenance and differentiation of pluripotent stem cell lines.

  • Working experience on iPSC derivation. Working experience on bovine iPSC derivation is a plus but not required.

  • In depth knowledge of early developmental biology and reproductive biology.

  • Experienced in the development of ESC/iPSC differentiation protocols.

  • Working experience with cell purification methods (FACS or similar technologies) required.

  • Hands-on experience with image-based, high-throughput screening.

  • Proven track record in process improvements and technical troubleshooting.

  • Strong oral and written communication skills and an ability to communicate complex concepts in a concise, simplified manner.

  • Demonstrated attention to details and ability to effectively manage own projects and priorities.

  • Supervisory/management experience a plus.

  • Experience using high-content, image-based software analysis systems is a plus.

  • Must be a team player and comfortable in fast-paced environment.

EOE MFDV


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Senior Scientist, Stem Cell Biology

Intrexon