Senior Scientist Oncology Pathology Biomarkers

About the Role

Location: Cambridge, MA (On-site, hybrid)

#LI-Onsite

About this role: The Oncology Translational Research (OTR) Department at the Novartis Biomedical Research in Cambridge, MA is a laboratory-based research group, which supports the development of novel therapeutics in the NIBR Oncology Disease Area. Our group in Oncology Pathology Biomarkers (OPB) uses primarily tissue-based, cell-based, qPCR, and soluble protein assays to understand target epidemiology and biology, mechanisms of action, and response/resistance biomarkers, ranging from early stages of target identification through late-stage clinical trials.

We are seeking a motivated Senior Scientist who will work within a sub-team of OPB, primarily passionate about tissue-based biomarker assay development (e.g., IHC, ISH, and FIHC) for eventual transfer to external contract research organizations as part of clinical trials or for exploratory research on preclinical and consented clinical and commercial samples. The Senior Scientist will help support programs across a wide range of therapeutic modalities and disease indications within Oncology and have opportunities to develop additional skills in image analysis and participate in technical development within OPB.

Key responsibilities:

• Complete experiments and procedures requiring specific scientific or technical knowledge and laboratory techniques, such as immunohistochemistry, immunofluorescence, and in situ hybridization.

• Implement experimental steps and existing lab techniques according to established laboratory protocols with some input from senior lab members/manager.

• Develop multiplex IHC, FIHC and ISH using automations.

• Provide basic data analysis: report experimental hypothesis, experimental details, summation of raw data, graphs and statistical analysis.

• Conduct image analysis of whole slide images using established platforms.

• Deliver high‐quality data to impact drug discovery and projects in clinical development.

• Ability to independently design and interpret experiments and plan next steps with support from matrixed collaborators

• Experience working with cross-functional teams and serving as a point-of-contact for the team

Diversity & Inclusion / EEO

We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:

• Novartis: e-mail [email protected] or call +1 (877)395-2339

• Sandoz: e-mail [email protected] or call: +1-609-422-4098

Role Requirements

Essential Requirements:

• Minimum of BS and MS preferred in the Biological Sciences or related field.

• 3 years of professional laboratory experience in academia or industry.

• Experience with basic molecular and cell biology techniques (cell culture, qPCR, western blot) and immunohistochemical and/or immunofluorescence techniques is required.

• Histology experience required.

• Basic computer proficiency (Excel, PowerPoint, Word) with ability and curiosity about new programs, such as image analysis platforms.

• Proven presentation skills.

Why Novartis: Our purpose is to reimagine medicine to improve and extend people's lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more here:

https://www.novartis.com/about/strategy/people-and-culture

You'll receive: You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook. https://www.novartis.com/careers/benefits-rewards

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

The pay range for this position at commencement of employment is expected to be between $92,800 and $139,200 / year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to hear more about Novartis and our career opportunities, join the Novartis Network here:

https://talentnetwork.novartis.com/network

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?