Sorry, this job is no longer accepting applications. See below for more jobs that match what you’re looking for!

Senior Scientist I, Immunology Discovery

Expired Job

Abbvie, Inc Cambridge , MA 02138

Posted 2 weeks ago

AbbVie Immunology is expanding its early discovery at Cambridge, Massachusetts. This new immunology research group at AbbVie Cambridge Research Center (ACRC) will focus on identifying new targets for the treatment of autoimmune and chronic inflammatory diseases through computational analysis of human disease tissue derived datasets, and validating targets using in vitro and in vivo experimental approaches. We are seeking a highly skilled and dedicated individual with immunology laboratory experience and bioinformatics expertise to partner with a functional genomics group and with in vivo pharmacologists to develop novel platforms for target selection and validation. This position requires passion, attention to detail, hands-on experience and teamwork.

Key responsibilities:

  • Identification and validation of novel targets for the treatment of inflammatory conditions.

  • Development of strategic plans to guide the selection and prioritization of identified targets.

  • Generate proof of concept data supporting target Go/No Go decisions using in vitro and in vivo platforms.

  • Conceptualize and execute novel approaches for target discovery and contribute to new technology development and platform building.

  • Planning and coordination of experiments with internal and external team members and facility operations.

  • Analysis and presentation of in vitro and in vivo study data, providing scientific interpretations and recommendations in lab meetings and project team meetings.

  • Maintaining accurate and well-organized records and laboratory notebooks.

  • Supporting development of protocols, study reports and data presentations.

  • BS, MS or PhD in Immunology/Biological Sciences or in a related discipline with 10+ (BS), 8+ (MS) or 0+ (PhD) hands-on experience working in a laboratory.

  • Expertise in the study of inflammatory diseases such IBD and/or other rheumatic disorders. Experience in human tissue processing is a plus.

  • Proficient in laboratory skills such as animal models, tissue handling for molecular and cellular phenotyping, multicolor flow cytometry and cell sorting, and gene and protein cellular and tissue expression.

  • Independent design, development and evaluation of well-controlled in vitro assays to address target biology and drug biology.

  • Experience in generating knockout, knockdown or enzymatically inactive target protein cell systems using approaches such as siRNA, shRNA and CRISPR for testing target validation hypotheses is desirable.

  • Excellent communication and organizational skills.

  • Must be a quick-learner and be a team-player.

Key AbbVie Competencies:

  • Builds strong relationships with peers and cross functionally with partners outside of the team to enable high performance.

  • Learns fast, grasps the "essence" and can change course quickly where indicated.

  • Raises the bar and is never satisfied with the status quo.

  • Creates a learning environment, open to suggestions and experimentation for improvement.

  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Equal Opportunity Employer Minorities/Women/Veterans/Disabled


See if you are a match!

See how well your resume matches up to this job - upload your resume now.

Find your dream job anywhere
with the LiveCareer app.
Download the
LiveCareer app and find
your dream job anywhere
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Senior Director Autoimmunity And Type 1 Diabetes Cluster Immunology & Inflammation Research Therapeutic Area

Sanofi

Posted 5 days ago

VIEW JOBS 9/15/2018 12:00:00 AM 2018-12-14T00:00 Senior Director, Autoimmunity and Type 1 Diabetes, Immunology and Inflammation Research Therapeutic Area Sanofi is building a world-class human immunology team and is seeking outstanding scientists with significant experience in immunology to help further develop our innovative pipeline in Type 2 Inflammation and Fibrosis, Autoimmunity and Type 1 Diabetes, Checkpoint Immunology, Innate Immunity and Precision Immunology. Job Responsibilities/Department Description: As a Senior Director of the Autoimmunity & Type 1 Diabetes Cluster in the Immunology and Inflammation Research Therapeutic Area you will develop and advance cutting-edge therapeutics by driving scientific innovation, excellence and rigor. The Senior Director of Autoimmunity & Type 1 Diabetes will manage a team of scientists based in Cambridge and will also lead research teams supported by multidisciplinary platforms and scientists based in the Boston area and around the globe. The Senior Director will identify and validate new targets working with experts within and outside their team using a variety of tools, including human immunology, human genetics, human sample analyses, bioinformatics, clinical data, and preclinical in vitro and in vivo models, implementing new models and technologies. The Senior Director of Autoimmunity & Type 1 Diabetes will work closely with research and development colleagues to ensure the progression of projects from concept to clinical testing, focusing on developing and validating impactful molecules with a strong translational rationale. The Senior Director will maintain a leadership position in immunology research communities, connecting Sanofi scientists with collaborators around the globe. The Senior Director will establish and manage productive collaborations with external scientists to help drive innovation. The Senior Director of Autoimmunity & Type 1 Diabetes will work closely with the Head of the Immunology and Inflammation Research Therapeutic Area to develop and integrate a research strategy within the broader Immunology and Inflammation Strategy, contribute to portfolio review and prioritization, and will be part of the Immunology and Inflammation Leadership Team, together with other senior leaders and key business partners. Key Accountabilities: ● Lead a Cluster/Department of scientists responsible for identifying novel targets and pathways to treat immune diseases in the area of autoimmunity and Type 1 Diabetes; connecting cutting-edge science with unmet medical need. ● Advance the Immunology and Inflammation Research Therapeutic Area strategy by identifying new targets and advancing projects in the current pipeline. Lead scientists experienced in a range of disciplines, from molecular and cell biology, immunology, genetics, and pharmacology, to develop deep mechanistic understanding of disease pathogenesis and confidence in target rationale, ● Lead internally and externally in an area of immune disease research, publishing cutting edge science and developing and maintaining key collaborations around the globe. ● Manage collaborative relationships with project leads, key internal and external stakeholders, and with the Sanofi research platform leadership to resource and advance portfolio projects. ● Recruit, retain and develop world-class scientific talent. Essential Qualifications: ● PhD or MD/PhD with postdoctoral and/or fellowship training. 12+ years of experience developing and leading research programs. 12+ years of experience in drug discovery and development or equivalent academic experience preferred. Preferred Qualifications: ● Deep expertise and outstanding record of research and publications in immunology. ● Expertise in extending discovery research through translational human biology to clinical development, using human biology approaches, biomarker development and validation, and forward and back translation of research and clinical endpoints. ● Experience leading multi-disciplinary, matrixed teams. ● Understanding of complex research landscapes globally, ability to identify cutting-edge research and new directions, and connect internal and external colleague productively. ● Outstanding management, communication and interpersonal skills. ● Experience with multi-cultural teams and environments. ● Fluency in French and German is a plus. #LI-SA Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Sanofi, Empowering Life Apply for role Sanofi Cambridge MA

Senior Scientist I, Immunology Discovery

Expired Job

Abbvie, Inc