Senior Scientist I, Biologics

Abbvie, Inc Worcester , MA 01601

Posted 2 months ago

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.

AbbVie Global Biologics and Virology Research is an integrated, global discovery organization responsible for anti-viral drug research across indications including HIV AIDS, Hepatitis C, and emerging viral syndromes such as SARS-CoV-2. Our scope includes the discovery of innovative small molecule and biologic medicines from the early exploratory stage and their support through clinical development. We are growing a world-class team of scientists and leaders who will drive the discovery and advancement of innovative anti-viral and biologic-based therapies. Careers in AbbVie Global Biologics and Virology provide unique opportunities to work with cross-functional teams that drive exceptional science and deliver innovative medicines to patients. We are looking for diverse candidates with strong scientific and leadership experience to join the team and can offer exciting and rewarding career opportunities for these candidates.

The candidate will apply state-of-the-art computational tools to the design and optimization of new therapeutic biologics molecules, using different conformational search methods to investigate the structure-function relationship of biologics, and develop new methods for calculating biomacromolecular interactions.

Major Responsibilities:

  • Routinely demonstrate scientific initiative and creativity in research or development activities.

  • Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.

  • Formulate conclusions and design follow-on experiments based on multidisciplinary data.

  • May initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research or development program.

  • A primary author of publications, presentations, regulatory documents and/or primary inventor of patents.

  • Demonstrates high proficiency across a wide range of relevant technologies.

  • Maintain a high level of productivity in the lab.

Qualifications

  • PhD, MS or BS in computational chemistry, computational biology, biophysics or related discipline with typically 0+ (PhD), 8+ (MS) or 10+ (BS) years of relevant post-degree experience.

  • Experience with molecular dynamics and/or Monte Carlo simulations, ideally on biomacromolecules.

  • Experience in docking is preferred but not required.

  • Experience in protein chemistry and biophysical characterization.

  • Familiarity with UNIX operating system and scripting and programming languages, including but not limited to C, Python, R, Perl.

  • Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.

  • Demonstrated ability to learn, understand and master new experimental techniques.

  • Ability to multitask and work within timelines.

  • Demonstrated scientific writing skills and strong verbal communication skills.

Significant Work Activities

N/A

Travel

No

Job Type

Experienced

Schedule

Full-time

Job Level Code

IC

Equal Employment Opportunity

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

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