Senior Scientist, Cell Biology (Epigenetics)
Req #: 1803008
Location: San Diego, CAUS
Job Category: Research and Early Development
Work Location: 10300 Campus Point Drive Suite 100 SIGSD 92121
Employee Status: Full time
Job Type: Regular
Other Locations:US- CA- San Diego
Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.
We are seeking a highly motivated scientist to join our Epigenetics Center of Excellence. Reporting to the Director / Epigenetic Drug Discovery Head, the candidate will be based in San Diego, CA. He/she will be expected to design, plan and execute biological studies for identifying new targets and to support drug discovery projects from target identification to nomination of development candidates. This role will work closely with other functions such as Bioinformatics, Biochemistry, Chemistry and Pharmacology to coordinate the progress of projects. With an emphasis in Oncology, the scope of work will cover also Immuno-Oncology, Inflammation and Neurodegenerative diseases. It will involve collaborative work with academic centers and business partners as well.
The successful candidate will have a strong foundation in transcription regulation in cancer with previous experience in Drug Discovery.
Ph.D. in Biology or related scientific discipline with at least 6 years of relevant cancer research experience, preferably in Industry
Proficient in cell biology including shRNA and CRISPR technologies
Experience in target validation, functional and biomarker cell-based assay development.
Experience in performing and/or interpreting epigenetic profiling studies is highly desired (DNA methylation, RNA-sequencing, ChIP-sequencing and ATAC-sequencing).
Solid experience in Drug Discovery.
Highly motivated, innovative and strong team player. Experience to work in a cross-functional team
Excellent time management and organizational skill.
Strong communication skills, both written and oral.
Strong ability to work in a fast-paced environment is essential.
Strong interpersonal and communication skills with a demonstrated ability for creative thinking and problem solving.
Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.