Senior Scientist, Assay Development

KSQ Therapeutics Cambridge , MA 02139

Posted 3 weeks ago

About KSQ Therapeutics

At KSQ Therapeutics, we seek to understand the role of every human gene in each disease, each tissue, and each cell that we study. This comprehensive approach has resulted in a massive, experimentally derived dataset that we have found to be remarkably predictive of past successes and failures in oncology and immuno-oncology product development. Utilizing this approach, we also identified a number of opportunities for the development of new medicines. As a result, we have aggressively invested in these distinct, highly validated pathways for new drug development with the expectation that the medicines we create may become the next breakthrough products for patients.

Founded in late 2015, KSQ is a preclinical-stage biotech in Kendall Square that has rapidly advanced the field of CRISPR-enabled functional genomics, from in vitro cell autonomous screens to more complex genome-scale screens of immune cells in vivo. The company has expanded the scope of its technology to include multiple cell types and to unlock areas beyond oncology. KSQ is led by a team of accomplished industry experts in drug discovery and development. We maintain a lively and inquisitive environment in the heart of the vibrant Kendall Square (KSQ) neighborhood.

Position Summary:

KSQ Therapeutics, Inc. is seeking a highly motivated Senior Scientist with a strong background in assay development to join our Oncology group. The successful candidate is expected to collaborate across our research groups to identify biomarkers and lead the development of cell-based assays to support drug discovery campaigns.

Requirements

  • BS/MS with 5-10 years of experience in industry drug discovery setting, preferably in cell-based assay development
  • Familiarity with both targeted oncology and immuno-oncology assays preferred
  • Ability to identify, develop and validate biomarkers to support drug discovery programs
  • Experience with a wide range of assay techniques such as ELISA, HTRF, MSD, Luminex, Flow cytometry, NanoString, qPCR, Western blotting
  • Coordinate and manage assay transfer to external CROs if necessary, including all technical documentation and necessary control samples for validation of assay
  • Independently motivated, excellent communication and organization skills and the ability to work in fast paced, highly collaborative environment
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Senior Scientist, Assay Development

KSQ Therapeutics