This Senior Research Scientist II/Principal Scientist will join the Immune Resistance Biology Research Team at Bristol-Myers Squibb in Cambridge, MA to support preclinical drug development against therapeutic targets at the intersection of tumor genetics and tumor immune biology.
The qualified candidate is a highly motivated, interactive, and creative individual who possesses substantial experience in studying tumor biology and genetics, and experience or strong interest as to how these features impact immune responses to the tumor. Since BMS is a matrixed organization, the candidate will be expected to effectively collaborate with colleagues in supportive line functions (including oncology, immuno-oncology and immunology, medicinal chemistry, candidate optimization and translational medicine) to advance preclinical development of therapeutic candidates to early clinical development.
The opportunity to gain experience in biologics preclinical drug development will be available. The successful candidate will demonstrate clear and professional verbal and written communication, capable of presenting scientific results to multidisciplinary teams, senior management and at external scientific meetings. The candidate will develop external partnerships/collaborations to advance internal programs, as appropriate. S/he will also manage a small in vitro biology lab to support their project responsibilities as well as to contribute to team held objectives, including new project and target ideas.
A Ph.D. degree with 4 to 8 years of industry experience (depending on level) in cancer biology and genetics or a closely related field is required. Industry experience is highly desired with demonstrated abilities to drive preclinical development from target ID to clinical candidate selection, especially experience in small molecules.
A proven track record in the field of cancer biology and genetics, as evidenced by publication record is required. Experience or the ability to innovate in novel preclinical in vitro, in vivo and ex vivo oncology model development that enables bridging from tumor biology to host immunity is highly desired. Demonstrated expertise to independently apply bioinformatics and data mining through multi-variate analysis; ability to effectively interact with core bioinformatics colleagues, as well as to use desktop tools/interfaces (e.g., Oncoland, Wuxi) and public databases (CBIO, Achilles, etc.) is required.
Management/supervisory experience is ideal, but not required. Excellent oral and written communication skills are required, as is the ability to effectively present scientific data and concepts to international standards. This position is located in Cambridge, MA. There will be less than 10-20% travel.
Bristol Myers Squibb