Senior Research Professor Of Pathology & Laboratory Medicine

Title Senior Research Professor of Pathology & Laboratory Medicine Specific Title Appointment Type Scientist Track Faculty Department IUSM - Pathology & Laboratory Medicine Campus IU School of Medicine Indianapolis Position Summary

The Indiana University School of Medicine has an exciting opportunity for Senior Research Professor (55% parttime) within the drug discovery and development team led by Drs. Chunhai "Charlie" Hao and Anita Bellail in the Department of Pathology & Laboratory Medicine. Successful Candidate will lead medicinal chemistry and drug development from lab to clinic.

Our team investigates targeted protein degradation for the discovery of small molecule degraders. The team has reported the first small molecule degraders of SUMO1 protein as novel anticancer drugs (Bellail et al. Science Translational Medicine 2021, 13:e12947). Recently, the team has also identified small molecule degraders of amyloid precursor protein (APP) as anti-aging drugs for Alzheimer's diseases ( https://doi.org/10.1101/2023.12.29.573648).

The position is supported by the team research fund including NIH grants. The salary is based on industrial experience in drug discovery and development and capped at the NIH Executive maximum level II and available for an initial appointment of one year, renewable for subsequent years.

IUSM is committed to being an institution that reflects the learners we teach and the patient populations we serve and pursues the values of equity and inclusion that inform academic excellence. We desire candidates whose work contributes to equitable and inclusive learning and working environments for our learners, staff, and faculty. We invite individuals who will join us in our mission to improve health equity and well-being for all throughout the state of Indiana.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences.

Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life - the city possesses a variety of professional sports, arts venues and outdoor recreation areas.

Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named "Best Airport in North America" by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation

Basic Qualifications

Applicants should have a Ph.D. degree in Synthetic Organic Chemistry or Medicinal Chemistry and have more than 15-year experience in pharma at senior executive levels.

• The candidates have demonstrated expertise in chemical design of compounds, synthesis, and optimization.

• The candidates have demonstrated records in development of compounds from bench to clinical trials.

• The candidates have demonstrated records in discovery and development of CNS drugs and anticancer drugs.

• The candidates have shown leadership in supervision and management of undergraduates, graduates, fellows, and junior faculty.

• The candidates have excellent written and oral communication skills and demonstrated ability to write peer reviewed quality work or invention disclosures for patent applications and scientific publications.

Department Contact for Questions

Sally Atcheson

Associate Director of Academic Research Administration

Department of Pathology and Laboratory Medicine

Additional Qualifications Special Instructions Priority Application Review Deadline Expected Start Date OAA # IUSM-01992-2024