Foundation Medicine is seeking a talented, highly motivated and results-oriented Senior Research Associate / Scientist I to join the Product Development Clinical Platforms group to support the late-stage development and deployment of new NGS-based assays in our clinical labs. The ideal candidate has research and clinical lab experience in a dynamic, multidisciplinary environment and a strong working knowledge of molecular biology, high throughput automation and next generation sequencing.
Work with a multidisciplinary team of scientists, engineers and computational biologists to support the late-stage development of clinical DNA-seq and RNA-seq diagnostic assays in our research and clinical labs.
Work to enhance existing and develop new automated workflows in collaboration with automation engineers.
Oversee the timely processing and reporting of oncology samples to internal and external collaborators.
Author detailed, accurate, and accessible records of experimental data and high-quality protocols.
Extensive experience with robotic liquid handlers, lab automation and instrumentation (especially from Agilent Technologies, Beckman Coulter or Hamilton).
Experience in standard molecular biology techniques and an understanding of the practices and principals of NGS, including DNA-seq and RNA-seq protocols, and various target-enrichment approaches (e.g. multiplex-PCR, hybrid selection).
Experience in the development and/or implementation of genomic assays in a regulated environment (CLIA, CAP, GxP, ISO, etc.) including writing standard operating procedures, validation protocols and data reports.
Results oriented with daily focus on working to achieve individual, project and group goals.
Scientific thought process and understanding of assay parameters illustrating creative approaches to problem solving to inform assay troubleshooting and optimization.
Education or Experience:
BSc required, MSc preferred.
Experience in Molecular Biology, Biochemistry, Genetics is preferred.
Minimum 3-5 years working in Industry and/or Academia.
Demonstrated ability to clearly communicate scientific results in internal and external presentations and publications.
Demonstrated ability to work independently and collaboratively in a dynamic, fast paced team environment.