Senior R&D Specialist (Autoimmunity, Neuroimmunology)

Regeneron Pharmaceuticals Tarrytown , NY 10591

Posted 2 months ago

Known for its scientific and operational excellence, Regeneron is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, atopic dermatitis and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including rheumatoid arthritis, asthma, pain, cancer and infectious diseases.

Summary:

We are looking for a Senior R&D Specialist position in the Immunology & Inflammation department with a focus on evaluating novel immune modulation mechanisms in the context of autoimmunity. Specifically, we are seeking a highly motivated, open minded, passionate and rigorous candidate with a background in cellular and molecular immunology, with hands-on experience and willingness to learn new skills to establish & characterize various autoimmune disease models, multicolor (>8) flow cytometry and analysis, co-culture assay systems; experience with single cell isolation and preparation for RNASeq profiling/sequencing data is highly desired. Ability to independently design, plan, execute experiments, maintain lab notebook, and communicate data in a timely manner is required. You will be part of a dynamic team, exposed to cutting edge technologies in the context of a scientifically fertile environment that tackles outstanding scientific questions looking for innovative solutions, while ensuring individual growth and development.

Job Duties:

  • Develops and optimizes relevant disease mouse models of autoimmune and inflammatory diseases, and the subsequent analysis of associated disease-related pathologies by flow cytometry, RNASeq, histology and ELISA, MSD

  • Develops and executes cell based assays to screen candidate antibodies for various research programs

  • Performs ELISAs and or MSDs to measure cytokine levels and determine antigen binding for various research programs

  • Experience with multi-parameter Flow cytometry and data analysis is required. Candidate will present analyzed data to supervisor and team

  • Contribute to project advancement by developing and refining new methods and technologies

  • Analyze data and interpret results of experiments within the context of research project goals, and work closely with supervisor to prepare and deliver effective oral presentations and papers in the area of expertise during internal and external meetings

  • Troubleshoots methodological and technical issues, interprets experimental data and literature, and communicates results to supervisor, department, or project team

  • Executes experiments based on projects/protocols provided and works towards independently developing project

  • Collaborates and communicates efficiently with team members to coordinate complex in vivo experiments, and with other departments to facilitate cross-functional efforts

  • Basic computer literacy and experience collecting and analyzing biological data on the computer is a necessity

  • Contribute to lab and equipment maintenance and order supplies/reagents to help create a safe, effective and efficient working environment

Requirements:

  • MS with in Immunology, Biology, Biochemistry, or related discipline with at least 6+ years of relevant lab research experience or BS degree with 8+ years of relevant experience

  • Experience with proper handling and care of mice, general surgical techniques and the collection of tissue samples and blood is required

  • Experience with mouse models of autoimmune or inflammatory disease is desired; experience in mucosal and/or neuro-immunology is a plus

  • Demonstrated hands-on experience with cellular and molecular biology techniques including isolation and culture of cell lines and primary cells (immune cells of human and mouse origin), experience with multi-cellular assays highly desired, multi-color flow cytometry, ELISA (MSD etc), functional assays (e.g. proliferation, cytokine production, etc.)

  • Maintain state-of-the-art laboratory equipment, and accurate and complete records in a timely manner

  • Able to multi-task and adapt to changing priorities and implement and develop new skills

  • Basic computer literacy and experience collecting and analyzing biological data on the computer is a necessity

  • Candidates will need to be highly organized and motivated with attention to the details

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron's unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

An important note about privacy: Regeneron is committed to your privacy and will not ask for sensitive personal information such as social security number, date of birth or bank account details via email or social media. We do not interview candidates on Google Hangouts. Any questions about job listings can be directed to candidatesupport@regeneron.com. We also do not hire for "at-home data entry" positions.


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Senior R&D Specialist (Autoimmunity, Neuroimmunology)

Regeneron Pharmaceuticals