Senior Pilot Plant Associate, Process Development (Contract)

Adverum is looking for a Senior Pilot Plant Associate to join our Process Development team in Redwood City. This individual will be a key member of the team, focusing on downstream activities.

This is a 6 month contract with an opportunity for an extension.

What you'll do: Perform pilot scale downstream purification process and manufacturing (post cell lysate to final formulation) by utilizing column chromatography, CsCl, UFDF, and various filtration steps.Follow good documentation practices to maintain accurate records.Work closely with team members to perform buffer preparation.Set-up, operate and maintain required downstream laboratory equipment.Maintain reagent, sample, and consumables inventory.Assist with data entry and data analysis in Excel and/or other statistical programs.Work closely with the downstream team to perform downstream experiments.

Ensure safe workplace in compliance with the company and EHS' rules and regulations.Work with Assay Development and Quality Control to coordinate testing.Work to identify optimize, revise, and update current process batch records, protocols, and procedures to make them more robust and streamlined.About you: Requires a Bachelor's degree (or higher) in chemical/biochemical engineering or related fields with 4+ years of downstream purification experience. Proficient in general and non-routine laboratory skills including aseptic technique, multi-channel pipetting and biosafety cabinet operations.Hands on experience with buffer preparations, TFF (Hollow Fiber/Cassettes), UF/DF and Column Chromatography Purification. Experience working with AKTA Avant is required.Requires some knowledge of GxP standards, and the ability to apply compliance principles to Adverum's laboratory practices.Able to work in a fast-paced environment as a team player with effective communication skills.Excellent computer skills; especially proficient in Excel and Word.Strong desire to learn new technologies, skill sets, and the science behind AAV processing.Strong teamwork and communication skills.Some overtime required, as needed.