Senior Manager, Compound Management

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

Montai Therapeutics is a privately held, early-stage biotechnology company developing a platform for understanding and leveraging complex molecular interactions within organisms to solve global challenges in human health and sustainability. The company leverages a multidisciplinary approach that integrates tools ranging from machine learning and big data to multi-omics and high-throughput screening.

At Montai, we nurture a bold, spirited, and leading-edge culture dedicated to strengthening human health:

• We are one team with omnidirectional trust, empowered and accountable

• We are strong as individuals but stronger as a team and we are committed to excellence

• We have a sense of urgency and persistence, and we are crazily confident that we can make a difference

• We need to be comfortable with the uncomfortable and be rigorous and we recognize that failure is data

• We care for diversity in people, thought, personality, opinions, background and distinctiveness

• We have a sense of humor to help us manage through our strategic noise

Position Summary

Montai Therapeutics is seeking an experienced Senior Manager to oversee our Compound Management function. This individual will help manage and grow Montai's small molecule compound library and inventory management systems in support of our screening campaigns and lead optimization projects. The successful candidate will have substantial experience in all aspects of compound management in a fast-paced, small-molecule focused drug discovery environment. The role will involve close collaboration with the biology, chemistry, and project teams to ensure they have rapid access to Montai's chemical inventory as compounds progress from screening campaigns through lead optimization and development candidate nomination. Furthermore, the successful candidate will have excellent communication and collaboration skills, knowledge of R&D processes, and experience managing external CROs'

Responsibilities

• Maintain strong business and operational relationships with compound management and chemical sourcing vendors to ensure competitive service levels and pricing

• Drive implementation of industry best practices for library storage, reformatting, cherry picking, transport, QC

• Ensure that compounds are maintained at appropriate stock levels according to program needs (e.g. core screening library, advancing hits, reference controls, scale-up intermediates)

• Work closely with drug discovery teams to ensure that compounds efficiently get into assays to drive overall speed in our assay cascades

• Work closely with data teams to ensure we have robust analytics on our library

• Coordinate with synthesis and commercial partners to manage procurement and registration of compounds

Qualifications

• BA/BS or MA/MS in Chemistry, Biology, Pharmacology, Biotechnology or related disciplines

• 5+ years of experience in industrial Pharmaceutical/Biotech setting supporting HTS and management of small molecule chemical collections - work in core facilities is preferred

• Fluent in industry standards and best practices for compound management technologies and methodologies including but not limited to:

• Chemical storage conditions

• Liquid handling and common container types across nL and uL and mL volumes

• Handling of neat powders and films at mg, g and kg scales

• Domestic and international shipping of research compounds

• Inventory software

• Basic cheminformatics

• Excellent verbal and written communication skills to independently drive successful partnerships with internal and external stakeholders

• Diligent organization skills to manage many simultaneous work streams and keep diverse projects on track

• Be able to report status and timeline on key deliverables to senior leadership regularly

More About Flagship Pioneering

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity's most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE's "Change the World" list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company's annual list of the World's Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, "FSP") do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.