Senior Manager, Cell & Gene Therapy Applications

Thermo Fisher Scientific Inc. Carlsbad , CA 92008

Posted 2 months ago

Apply

This Job is not relevant Tell us why

Job Description:

Title: Cell and Gene Therapy/Associate Director

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. Our global team of more than 75,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon. For more information, please visit www.thermofisher.com.

How will you make an impact?

The Cell Therapy application group is looking for an exceptional person who is proficient in a variety of cell biology related techniques, from isolation to engineering, expansion to analysis. We are looking for someone dedicated to make a positive impact in Cell therapy by developing new innovative cell therapy manufacturing systems that will enable our customers to develop the therapies of tomorrow and make them accessible to all. We are looking for an individual who is talented scientifically, has extensive biological experience, has a strong work ethic a sense of urgency and has the ability to manage a multidisciplinary team and manage a large number of external collaborations. This position requires excellent organizational skills, independence, enthusiasm and the ability to work in a highly collaborative environment.

What will you do?

Lead a group of application scientists to develop workflow solutions related to cell therapy manufacturing.
Integrate platforms and reagents into an automated solution, working closely with process and software engineers
Manage project scope, budget and schedule to achieve timely completion of project deliverables.
Give customer presentations and manage collaborations at a technical level
Develop Scale up protocol for different bioreactors (Wave, Spinners, others)
Launch product using a gated approach
Support process transfer to customers
Author technical documents and PPT presentation

How will you get here?

Demonstrated experience with the development of bio-processes for cell therapy preferred.
Experience in Design of Experiments and statistical analysis.
Experience with analytical techniques preferred.
Ability to work independently in a fast paced team environment, meet deadlines, prioritize work across multiple projects.
Self-starter with strong work ethic.
Must have excellent organizational, attention to detail, verbal and written communication skills.
Proven ability to identify strategic opportunities, set aggressive objectives, and drive key business priorities.
Willingness to do what needs to be done in a dynamic environment
Experience developing and presentation materials for sales training, customer interaction and executive presentations.

Education Requirements

Ph.D. or equivalent and 5- 6 years of experience or B.S. with at least 10+ years of relevant experience, preferably in industrial setting.

At Thermo Fisher Scientific, each one of our 75,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission-enabling our customers to make the world healthier, cleaner and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Show Full Description

See how you match
to the job

Upload my resume

Download the
LiveCareer app and find
your dream job anywhere

Similar Jobs

View All

Want to see jobs matched to your resume?
Upload One Now!

Applications Scientist Iii Cell And Gene Therapy R&D

Thermo Fisher Scientific Inc.

Posted 3 weeks ago

VIEW JOBS Job Description Job Title: Applications Scientist III, Cell and Gene Therapy R&D Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. When you are part of the team at Thermo Fisher Scientific, you'll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you'll be supported in achieving your career goals. Location and Division Specifics The Cell & Gene Therapy R&D team focuses on developing and improving products and workflows to meet customers' needs. Working together with R&D teams from other disciplines ensures an energetic and fast paced environment to drive collaboration and scientific curiosity. How will you make an impact? This position requires a talented and motivated scientist to support cell and gene therapy product development initiatives. The role will focus on building cell and gene therapy relevant workflows integrating new cell processing and gene delivery platforms. Work includes both ex vivo and in vivo gene delivery and genetic engineering of primary T cells, NK cells and hematopoietic stem cells with viral and non-viral platforms. The ideal candidate will also have knowledge and experience in closed automated systems, cell therapy process development and clinical manufacturing. Additionally, it is expected that this individual will be able to work collaboratively with other scientists and cross-functional project team members including engineers, product management, marketing and commercial team to support the development and launch of new products. What will you do? * Critically design, plan and independently execute experiments, * Isolation, expansion and maintenance of human immune cells including T cells, NK cells and other relevant cell types * Execute experiments using automated cell therapy instrument platforms * Optimize ex vivo gene delivery protocols to maximize gene editing in immune cells and stem cells * Some in vivo gene delivery into mouse models with viral vectors * Perform analytical assays including identity and potency assays as well as complex multi-color flow cytometry experiments to characterize and validate cell types of interest * Work collaboratively with other R&D colleagues and product application scientist to integrate newly developed cell processing and gene delivery platforms to develop closed automated workflows * Actively working with cross functional team to identify new cell and gene therapy product and workflow automation opportunities * Build and maintain good lab notebooks, protocols and SOPs How will you get here? * Ph. D in cell biology, immunology or relevant life sciences field with 1-2 years or Masters with 3-5 years of relevant industry experience * 3+ years of immune cells and at least 1-2 years of cell therapy instrument platform is required. * Experience in viral or non-viral genetic modification is preferred. * Extensive cell analysis and characterization assay experience especially with immune cells and stem cells with minimum 2 years multicolor flow cytometry * Demonstrate a sense of urgency with a can-do attitude to take on new tasks * Self-starter with strong work ethic and ability to work independently in a fast-paced team environment, * Must have excellent organizational skills, attention to detail, verbal and written communication * Highly developed presentation skills to communicate results and needs to both internal and external team members At Thermo Fisher Scientific, each one of our 75,000 extraordinary minds have a unique story to tell. Join us and contribute to our singular mission-enabling our customers to make the world healthier, cleaner and safer. Apply today! http://jobs.thermofisher.com Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status

Cell And Gene Therapy Process Development Scientist III

Thermo Fisher Scientific Inc.

Posted 2 weeks ago

VIEW JOBS Job Description Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $25 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them. Our global team of more than 75,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services and Patheon. For more information, please visit www.thermofisher.com. Summary * The Cell Therapy application group is looking for an exceptional person who is proficient in a variety of cell biology related techniques, from isolation to engineering, expansion to analysis. We are looking for someone dedicated to make a positive impact in Cell therapy by developing new innovative cell therapy manufacturing systems that will enable our customers to develop the therapies of tomorrow and make them accessible to all. We are looking for an individual who is talented scientifically, has extensive biological experience, has a strong work ethic a sense of urgency and has the ability to manage a small group. This position requires excellent organizational skills, independence, enthusiasm and the ability to work in a highly collaborative environment. Demonstrates a sense of urgency, contagious optimism and a "can do" attitude. Is curious, inquisitive, innovative, never satisfied with the status quo. Greets challenge and change as opportunity. Collaborates with others and embraces and leverages diversity of culture and thought Responsibilities * Participate in development activities for new processes and procedures for human T cell therapy, including design of process scale-up/scale-out for isolation, activation, gene modification, expansion, harvest, formulation and fill/finish using automation and closed systems. * Integrate platforms and reagents into an automated solution, working closely with process and software engineers * Author and execute protocols, worksheets and/or SOPs to the levels that they are transferable internally to other Thermo Fisher Scientific sites and externally to customers. * Train and supervise junior scientist/specialist in the team. * Support process transfer to customers * Author technical documents and PPT presentation Required Qualifications * Demonstrated experience with the development of bio-processes for cell therapy preferred. * Experience in Design of Experiments and statistical analysis. * Experience with analytical techniques preferred. * Ability to work independently in a fast paced team environment, meet deadlines, prioritize work across multiple projects. * Must have excellent organizational, attention to detail, verbal and written communication skills. * Proven ability to identify strategic opportunities, set aggressive objectives, and drive key business priorities. * Willingness to do what needs to be done in a dynamic environment * Experience developing and presentation materials * Strong Biological background nd experience with immune cells isolation, engineering and culture Education Requirements Ph.D. in biochemical engineering, immunology, pharmaceutical or life sciences, or equivalent and 0-2 years of experience or M.S. with at least 4+ years of relevant experience, preferably in industrial setting. Minimum Qualifications . * Experience in T cell therapy workflow is required. Experience with cell therapy automation instruments/platforms is highly preferred. * Working experience in process development or manufacturing setting is highly desired. * Experience in cell therapy analytical assays, including identity, purity and potency, is preferred. * Experience in Immunology is highly preferred * Experience in viral or non-viral genetic modification is preferred. * Ability to work independently in a fast-paced team environment, meet deadlines, prioritize work across multiple projects. * Self-starter with strong work ethic. * Must have excellent organizational, attention to detail, verbal and written communication skills. * Anticipates needs and problems while creating solutions Working Conditions: Works in a laboratory environment. Is required to lift up to 40 lbs. May be required to stand for long periods of time while performing duties. Must be able to work safely with chemicals and hazardous materials. Must be able to work overtime and flexible shifts.

Lab Manager/Scientist I Cell And Gene Therapy

Thermo Fisher Scientific Inc.

Posted 3 weeks ago

VIEW JOBS Job Description When you're part of the team at Thermo Fisher Scientific, you'll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you'll be supported in achieving your career goals. How will you make an impact? The Cell Therapy application group is looking for a talented and highly motivated candidate to join our application team as lab manager at our Carlsbad site. This position offers the opportunity to contribute to the product design and development of Cell therapy systems supporting a broad range of research and regulated applications. Is curious, inquisitive, innovative, never satisfied with the status quo. Greets challenge and change as opportunity. Collaborates with others and embraces and leverages diversity of culture and thought. What will you do? * The successful candidate will ensure that the CGT lab maintains best-in-class processes and standards for the development of Cell therapy regulated products. * As a Lab Manager, you will be the point-of-contact and subject matter expert for all laboratory management-related activities and will partner with cross-functional teams including R&D, Operations, Compliance, Quality and Regulatory to facilitate new product development efforts in both research and clinical settings. * Perform supply logistics which includes forecasting and procuring materials for R&D demand and inventory control * Manage laboratory day-to-day operations including lab organization (5S), laboratory facilities, lab accessibility and security, and safety protocols. * Perform equipment life cycle asset management duties including maintaining instrument calibrations and validations, servicing laboratory equipment, and managing a validated equipment and asset database. How will you get here? Education * High school diploma or equivalent required. * Bachelor's degree in Molecular Biology, Chemistry or equivalent disciplines preferred Experience * Experience working in ERP systems and working with computer databases. * Management Experience - may be required tom manage lab support personnel Knowledge, Skills, Abilities * Knowledge in clinical lab protocols and laboratory equipment and supplies. * Able to self-manage and work both independently and in coordination with R&D, Operations, and Quality teams. * Experience running projects with multi-functional teams while adhering to tight deadlines in a fast-paced environment. * Practical Process Improvement (PPI) * Document Change Control * Excellent attention to detail in record keeping and documentation * Able to communicate at all levels of the organization including managers and senior leaders in the organization.

Apply