Scientist/Senior Scientist, Omni-Biomarker Development, Development Sciences

Genentech South San Francisco , CA 94080

Posted 3 months ago

The Position

We are seeking a highly motivated Scientist or Senior Scientist to join the OMNI-Biomarker Development Department within Development Sciences to drive our biomarker and drug development efforts in multiple sclerosis. Our department is responsible for defining biomarker and personalized healthcare strategies, designing and implementing biomarker assays in clinical trials, and interpreting biomarker results.

Our group uses relevant biomarkers to evaluate disease heterogeneity, target-engagement, mechanism of action, and disease modification; and to guide clinical diagnostic biomarker development. Biomarker team leaders within the department provide scientific leadership for biomarkers in clinical trials ranging from early proof-of-concept through marketed products.


The successful candidate will join our dynamic team and work to identify biomarkers in support of drug development projects in multiple sclerosis.

The candidate will support multiple trials, lead efforts for data generation and analyses within internal studies and as part of external academic collaborations relating to understanding biomarkers in multiple sclerosis.

The successful Scientist will have the opportunity to grow into a project biomarker team leader. Success in these responsibilities requires a thorough understanding of disease and drug target biology, creativity and attention to detail, and experience in integrating biomarkers into clinical trials. Candidates familiar with molecular/immunological techniques and analytic methods including immunoassay, qPCR, genetics, gene expression analysis, cellular immunology, or analytics (knowledge of R or other data analysis programming experience) will be given preference.

The position requires working in close partnership across various functions including Research, Bioanalytical Assay Department, Diagnostics, Clinical Sciences, Biostatistics, Bioinformatics, Regulatory and with external partners. Effective communication is essential and includes presentations at cross-functional teams, internal review committees, and external conferences, and will also involve writing biomarker sections of clinical protocols, reports, regulatory filings and scientific publications.

Who You Are

Candidates must have a PhD or MD in Neurology, Neuroscience and/or Immunology, or a related field with at least 3 to 5 years of post-doctoral or fellowship experience in basic or translational research either in an academic and/or industry setting. The candidate must demonstrate a high level of independence and be able to develop hypotheses and direct analysis plans.

Strong writing and communication skills are required, as evidenced by publications, meeting abstracts and/or drug development reports. We are looking for an individual who would be passionate about using their understanding of disease biology to make impactful contributions to clinical drug development. Willingness to collaborate across time zones including our Swiss site is a must. Preferred candidates will have prior experience in multiple sclerosis and a demonstrated ability to function as part of a cross-functional team such as research or clinical trial project teams.




icon no score

See how you match
to the job

Find your dream job anywhere
with the LiveCareer app.
Mobile App Icon
Download the
LiveCareer app and find
your dream job anywhere
App Store Icon Google Play Icon

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Senior Scientist Oncology And Inflammation Biomarker Discovery

Amgen Inc.

Posted 6 days ago

VIEW JOBS 1/12/2020 12:00:00 AM 2020-04-11T00:00 Career Category Research Job Description Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing a Biomarker-Discovery group to support therapeutic programs. The Amgen Inflammation & Oncology Research Group is looking for a Scientist dedicated to biomarker discovery in the areas of immuno-oncology and inflammation. In this role you will work cross-functionally and interact closely with both the clinical biomarker and discovery research groups. The position will focus on the discovery of biomarkers to support the progression of therapeutic candidates from discovery to early clinical development. The role is responsible for: Developing deep disease area expertise for key indications in the therapeutic area's strategy Discovery and prioritization of disease stratification and target engagement biomarker candidates relevant to the pipeline Developing, implementing, and executing a therapeutic biomarker discovery strategy across several programs Generating and transitioning key pharmacodynamic and patient stratification/selection biomarker discovery data in support of clinical biomarker assay and companion diagnostic test development Supporting translational biomarker activities for therapeutic assets including investigator meetings/ad boards and investigator sponsored studies for correlative biomarker research together with the Clinical Biomarker lead The role is expected to work in a highly matrixed environment to drive scientific and technical innovation collaboratively with other members of the Inflammation & Oncology group, as well as with other functions including the Clinical Biomarker & Diagnostics Team, Translational Medicine, Therapeutic Discovery, Human Genetics and Computational Biology. Basic Qualifications Doctorate degree and 2 years of scientific experience OR Master's degree and 5 years of scientific experience OR Bachelor's degree and 7 years scientific experience Preferred Qualifications PhD or MD, with postdoctoral training and research experience in the fields of immunology, oncology and/or cancer immunotherapy Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology and/or oncology as demonstrated by multiple high impact publications Demonstrated experience in leading independent research and drug development Experience with implementing multiple technology platforms Experience with computational biology Strong verbal and written communication skills. Ability to collaborate and troubleshoot to solve problems Experience working in teams and consistently delivering results At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business. Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include: * Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams * Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities * Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business * Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement * Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages * Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans A Fortune 150 company operating in nearly 100 countries around the world, we invest in highly skilled, dedicated and collaborative individuals who are ready to contribute to our mission in meaningful ways and make a difference in the lives of our patients. That's why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Focused on the industry's most compelling scientific discoveries and housed within industry leading facilities within the heart of the world's leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses. Join Us If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance. Amgen Inc. South San Francisco CA

Scientist/Senior Scientist, Omni-Biomarker Development, Development Sciences