Scientist: Pharmacodynamics (Pd) / Translational Science (Ts)

Scientist: Pharmacodynamics (PD) / Translational Science (TS)

Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We are an oncology-focused biopharmaceutical company leveraging deep cross-discipline expertise to discover highly differentiated therapies and develop a broad portfolio of novel combinations addressing significant unmet needs.

Overall description:

This position in the Pharmacodynamics (PD) team offers a unique professional opportunity to gain in-depth exposure to industrial drug discovery and development from a proven research team. The PD group is focused on the development and execution of assays to evaluate engagement of our drugs and their biological effects in patient samples. Our role within the Translational Science (TS) department is a central element of our clinical research engine and we have a position available to work on-site at our headquarters in Hayward, CA.

The ideal candidate will have a working knowledge of immunology and direct experience with ELISA, MSD assays and flow cytometry techniques as well as the corresponding data analyses. Familiarity with assay validation/development, clinical sample handling, common molecular biology techniques, cell-based assays and lab management would be advantageous. This position requires a motivated candidate who can work independently and has strong organizational and communication skills, attention to detail, an aptitude and enthusiasm for collaboration, maintaining high quality data, and managing the integrity of our complex clinical trial datasets and sample records.

Responsibilities may include, but are not limited to:

• Planning and execution of PD assays on clinical patient blood-derived samples, including biochemical assays and immunophenotyping, i.e. MSD, ELISA, flow cytometry

• Development and validation of new assays as molecules move towards first in human (FIH) studies

• Biological sample banking, including isolation of serum, plasma or nucleic acids from human blood samples

• Clinical sample database management, including routine accessioning and record-keeping pertaining to barcoded patient samples

• Working with a team of PD scientists and other researchers to complete daily routine laboratory work and integration of results to ensure consistent and timely delivery of high-quality data

• Collaborating, contributing ideas and coordinating with other research groups, such as Biology, as potential therapies move from compound characterization to clinical development

• Analyzing, interpreting and effectively communicating scientific results in a coherent and timely manner

• Contributing during lab meetings and assisting in the analysis and reporting of experimental data to project teams

Qualifications:

• PhD degree with 0+ years experience or MSc with 5+ years experience in immunology, cell biology, biochemistry or related field, preferably in an industry setting. Title and salary is commensurate with experience.

• Proven laboratory and analysis skills with precision, including experience with common cell biology techniques and 96-well plate assays such as ELISA/MSD

• Exceptional precision, attention to detail and organizational skills

• Willingness to learn and adapt quickly in a fast-paced environment to deliver on time-sensitive objectives

• An aptitude for critical thinking, process optimization, and assay development

This role is based at our Hayward, CA location. The anticipated salary range for fully qualified candidates applying for this position is $125,000 - $165,000 USD annually. This salary range is an estimate of what we reasonably expect to pay for this posted position. The actual salary may vary based on various factors including, without limitation, individual education, experience, tenure, skills and abilities, internal equity and alignment with market data. In addition to a competitive market-based salary, Arcus offers the opportunity to participate in stock programs, a performance-based bonus, and a comprehensive benefits package. Additional information about our total rewards program can be found here: https://arcusbio.com/careers.

EOE

Arcus Biosciences is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Arcus is committed to the principle of equal employment opportunity for all employees and does not discriminate based on race, religion, color, sex, gender identify, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other legally protected status. EOE/AA/Vets

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