Scientist, Molecular Biology

Recruitomics Consulting Cambridge , MA 02142

Posted 2 weeks ago

Company Summary:
VL58, Inc. is a privately held, early-stage biotechnology company developing a novel approach to gene editing and gene therapy that can address diseases that are untreatable with current approaches like CRISPR or AAVs.
VL58 was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Seres Therapeutics (NASDAQ:MCRB), Moderna, Syros Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture.
Position Summary:
The Research Scientist will be primarily responsible for the design and testing of new gene therapy and gene editing technology in mammalian cells. This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biologic drug discovery experience with pioneering discoveries driving a novel biological platform.
  • Designs libraries of proteins
  • Designs gene therapy and gene editing DNA vectors
  • Performs research and/or development in collaboration with others
  • Oversees research associates
  • Makes detailed observations, analyzes data and interprets results
  • Exercises technical discretion in the design, execution and interpretation of experiments that contribute to project goals
  • Prepares technical reports, summaries, protocols, and quantitative analyses.
  • Investigates, creates and develops new methods and technologies for project advancement
  • Maintains high level of professional expertise through familiarity with scientific literature and novel technologies
Preferred Qualifications (one or more):
  • Mammalian synthetic biology: DNA construct design for expression in mammalian cells
  • Synthetic protein design: altered protein structure by swapping functional domains, such as DNA binding domains like zinc fingers or TALs or effector domains like transcriptional activators.
  • Gene editing experience: using Cas9 or other approach therapeutically and quantitatively assaying editing efficiency and accuracy with state of the art technology.
  • Gene therapy experience: AAV, liposome-mediated delivery of DNA or mRNA.

Basic Qualifications:
  • Ph.D. in Biological Engineering, Genetics, Molecular Biology, or related field.
  • Post-doctoral research or 3+ years of industry experience is preferred.
  • A strong self-starter, independent thinker, with a strong attention to detail.
  • Demonstrated industry experience or academic achievement, as evidenced by publications in high impact journals or drug development is required
  • Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough manner.
  • Eager to work with highly-skilled and dynamic teams in a fast-paced, entrepreneurial and technical setting.
  • Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment.
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Scientist, Molecular Biology

Recruitomics Consulting