At the Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, what matters most is helping people live full and stabilized lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. We strive for partnership, and that has led to numerous breakthroughs. This includes medical miracles that have changed lives, to the simple consumer products that make every single day a little better. Our over 125,000 employees in 60 countries stand united in a common mission: To help people everywhere live longer, healthier, happier lives. Growing on a diverse company culture, celebrating the uniqueness of our employees and committed to diversity. Proud to be an equal opportunity employer.
The Biotherapeutics Development & Supply-Analytical Development (BTDS-AD) in Janssen is recruiting for a Scientist located in Malvern, PA. We discover and develop creative large molecule solutions to address significant unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.
The Analytical Development organization is continuing to build key scientific expertise in protein and vaccine characterization, and primary structure elucidation. We need a hardworking scientist willing to bring your expertise to exciting efforts in novel areas of protein characterization.
You will join the Primary Structure team within the Characterization group in the BTDS-AD department to conduct product characterization and process development activities. Your duties and responsibilities will include:
Operate state-of-the-art LC and MS instrumentation
Learn and utilize software packages for LCMS/protein analysis
Perform LCMS-based quantitation of post-translational modifications
Design and execute peptide mapping / MS experiments on monoclonal antibodies and proteins to assess sequence coverage and sites of modification
Contribute to IND, IMPD, BLA, and other regulatory filings
Develop/optimize assays, write protocols, reports
Coordinate testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
Lead or facilitate technical discussions and participate in cross-functional teams at project-related meetings
Looking for a result focused, hardworking individual who demonstrates excellent scientific knowledge and the highest standards. Do you love solving scientifically complicated problems? If so, you could be the person we are looking for. Additionally, you should have:
A Ph.D. in chemistry, biochemistry or a related field with 1~2 years of relevant industry experience, OR an MS with demonstrated ability is required
Hands-on experience with LC-MS/MS characterization of proteins is required
Proficiency at developing, optimizing and trouble-shooting assays is preferred
Experience maintaining high quality documentation, analyzing and accurately interpreting data, and preparing reports, and SOPs is preferred
Strong written and verbal communication and excellent social skills
A deep understanding and experience in the application of various GXP concepts is preferred
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
United States-Pennsylvania-Malvern-200 Great Valley Parkway
Janssen Research & Development, LLC (6084)
Johnson & Johnson