Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary blood tests, vast data sets and advanced analytics. The Guardant Health Oncology Platform is designed to leverage our capabilities in technology, clinical development, regulatory and reimbursement to drive commercial adoption, improve patient clinical outcomes and lower healthcare costs.
In pursuit of our goal to manage cancer across all stages of the disease, Guardant Health has launched two liquid biopsy-based tests, Guardant360 and GuardantOMNI, for advanced stage cancer patients, and is developing programs for recurrence and early detection, called Project LUNAR. Since its launch in 2014, Guardant360 has been used by more than 5,000 oncologists, over 40 biopharmaceutical companies and all 27 of the National Comprehensive Cancer Network centers.
To enable Guardant Health to lead the disruption of cancer treatments through non-invasive cancer screening, the Technology Development Team is seeking a highly motivated Scientist to lead the execution of sustaining and troubleshooting activities pertaining to our launched assays for rare variant studies with next-generation sequencing. At Guardant, we leverage the most advanced technologies and work with leaders in many different fields to create the most impactful and meaningful technologies for cancer management.
Duties and Responsibilities:
Identify areas for improvement in assay and propose and implement solutions
Design and perform experiments to continually improve our assay workstreams
Develop and perform longitudinal analytics of clinical lab performance and provide regular updates to cross-functional teams
Write experiment reports and update SOPs as needed
Collaborate cross-functionally with operations, process engineering, and bioinformatics to facilitate effective delivery sustaining and support deliverables
Lead in troubleshooting efforts with our Operations teams and capture lessons learned
Manage the escalation process between Operations and Technology teams
Conceptualize and perform feasibility studies on new assay improvements
Ensure all work is performed and documented in compliance with applicable regulatory and quality practices (FDA, ISO13485)
Be a mentor to grow junior team members
Present data, proposals, and progress in various forums and to technical and non-technical audiences
PhD degree in molecular biology, biomedical sciences, bioinformatics, genetics, biochemistry, or related field
Strong foundation in molecular biology techniques and NGS assay development, exemplified by publications, patent applications, or previous product development experience
Strong data analysis skills with experience with Python and R and the experience in handling large datasets
Demonstrated ability to organize, document and communicate scientific data
Sense of humor is a must
Consummate team player: demonstrated ability to contribute in an environment where numerous contributions are required to accomplish complex goals. Enjoy working independently and collaboratively in a fast-paced environment and able to adapt to change
Highly motivated and responsible self-starter and independent problem solver
Curiosity and drive
3+ years of industry work experience preferred
Product development in a regulated environment
Experience with assay development for automated liquid handling platforms
Experience in sustaining development or support
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Guardant Health, Inc.