Scientist Iii, Molecular Pathology

Boehringer Ingelheim Ridgefield , CT 06877

Posted 4 months ago

The Experimental Pathology group at Boehringer Ingelheim iscurrently seeking several talented Scientists for a new Molecular Pathology labwithin Non-clinical Drug Safety for Development at the Ridgefield, CT, site.Our team uses state-of-the-art tissue-based methods to support drugsafety evaluation. By integrating histopathology with current molecular andimaging techniques. This lab will provides novel biomarkers and enhancedbiological context for safety decisions.

Description:

Oversight of methodsdevelopment for all tissue based molecular endpoints (immunohistochemistry(IHC), in situ hybridization (ISH), laser capture microdissection (LCM), etc.). Primary responsibility for initiation andoversight of methods development for project required tissue cross reactivity(TCR)/TTP studies (includes scheduling, securing needed reagents, etc.);support for methods transfer for GLP studies (e.g., reagent shipments). Writesprotocols, methods and technical reports.

As an employee ofBoehringer Ingelheim, you will actively contribute to the discovery,development and delivery of our products to our patients and customers. Ourglobal presence provides opportunity for all employees to collaborateinternationally, offering visibility and opportunity to directly contribute tothe companies' success. We realize that our strength and competitive advantagelie with our people. We support our employees in a number of ways to foster ahealthy working environment, meaningful work, diversity and inclusion,mobility, networking and work-life balance. Our competitive compensation andbenefit programs reflect Boehringer Ingelheim's high regard for our employees

Duties & Responsibilities:

  • Primary responsibility for the oversight and conduct of methods developmentfor needed tissue cross reactivity studies; ensures all needed reagents and control materials are ordered andreceived from Research in a timely fashion, oversees labelling andcharacterization of labelled reagents as needed, supervises technical conductof methods development activities and provides input to ensure methods areoptimized and "fit for purpose", writes method development reportsfor transfer to Contract Research Organization (CRO) for validation accordingto Good Laboratory Practices (GLP). Works independently.

  • Develops, conducts and/or optimizes novel tissue/cell based assays tosupport incorporation of improved safety or mechanistic endpoints into NDSnon-clinical safety evaluations. Proposes new assays, techniques, or approachesbased on current information.

  • Documents all work activities and maintains all assigned study recordsaccurately, completely and in accordance with study protocols by followingapplicable company policies, using current forms and procedures, and making allentries legibly, correctly and contemporaneously.

  • Performs all work safely and in compliance with all applicableregulations, SOPs, company policies, safety training and procedures.

Requirements:

  • One of the following is required: Bachelor's Degree from an accredited institution with 10 years of experiencein a relevant scientific discipline; A Master's Degree from an accreditedinstitution with six-plus (6 ) years of experience in a relevant scientificdiscipline

  • Histotechnician (HT)/Histoechnologist (HTL) with Qualification inImmunohistochemistry (QIHC) or eligible with 10 years' experience in immunohistochemistryand/or in situ hybridization methods development in a laboratory environment.

  • Hands on experience in assay development and optimization, data analysisand interpretation.

  • Knowledge and experience in the principles and approaches for developmentof Immunohistochemistry (IHC), in situ hybridization (ISH) assays

  • Knowledge and experience in the principles and approaches for developmentof antibody reagent characterization, cataloging

  • Laboratory management experience.

Eligibility Requirements:

  • Must be legally authorized to work in the United States without restriction.

  • Must be willing to take a drug test and post-offer physical (if required)

  • Must be 18 years of age or older

Our Culture:

BoehringerIngelheim is a different kind of pharmaceutical company, a privately heldcompany with the ability to have an innovative and long term view. Our focus is on scientific discoveries thatimprove patients' lives and we equate success as a pharmaceutical company withthe steady introduction of truly innovative medicines. Boehringer Ingelheim is the largest privatelyheld pharmaceutical corporation in the world and ranks among the world's 20leading pharmaceutical corporations. AtBoehringer Ingelheim, we are committed to delivering value through innovation. Employees are challenged to take initiativeand achieve outstanding results. Ultimately, our culture and drive allows us tomaintain one of the highest levels of excellence in our industry. Boehringer Ingelheim, including BoehringerIngelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer IngelheimAnimal Health USA, Inc. and Boehringer Ingelheim Fremont, Inc. is an equal opportunity employer - Minority/Female/ProtectedVeteran/Person with a Disability

BoehringerIngelheim is firmly committed to ensuring a safe, healthy, productive andefficient work environment for our employees, partners and customers. As part of thatcommitment, Boehringer Ingelheim conducts pre-employment verifications and drugscreenings.

#LI-SS1


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Scientist Iii, Molecular Pathology

Boehringer Ingelheim