Scientist Ii/I, Immunology (Macrophage Cell Therapy)
Boston , MA
Posted 3 weeks ago
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BlueRock Therapeutics, Cambridge location is expanding, and a key position to be hired is a Scientist II/I, Macrophage Cell Therapy within the Immunology group. This role will contribute to discoveries and preclinical development of macrophage cell therapies under the direction of a lead scientist. The ideal candidate will have a combination of experience in auto/allo/iPSC cell therapy, inflammation, and macrophage/myeloid immunology, but candidates with strengths in specific categories will be considered. This position is an outstanding opportunity for a talented and self-motivated scientist to develop cutting-edge cellular therapies.
- Under supervision, develop cell-based assays and molecular tools to advance macrophage cell therapy programs
- Execute key in vitro and in vivo assays to interrogate macrophage biology
- Analyze macrophage phenotype and function by multicolor flow cytometry, ELISA, gene expression analysis, and other cell and molecular techniques
- Responsible for designing studies, executing experiments, generating, and collecting data, and communicating the results effectively
- Document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system
- Attend and present data at lab meetings and other forums
- Contribute to building a culture that embraces scientific excellence, integrity, urgency, community and self-improvement.
- Perform additional duties to support the safe and efficient operation of the laboratory, and other duties as assigned.
- Ph.D. in Immunology, Cell Biology, Immuno-oncology, Autoimmunity or related discipline with at least 0-2 years of research experience in academia and/or industry is required. Candidates with a Bachelors degree in related discipline with 10+ years of relevant experience or a Masters degree in related discipline with 9+ years of relevant experience are equally encouraged to apply.
- Demonstrated expertise in innate immunology, immuno- oncology, macrophage biology, inflammation or cell therapy is preferred
- Hands-on expertise with macrophage and/or immune cell culture, immune cell functional assays, with experience in primary human immune cell co-culture, immune cell differentiation, and/or flow cytometry cell phenotyping desired
- Effective communicator with excellent interpersonal and organizational skills is required
- Proficiency in analysis, presentation, and documentation of scientific data as well as preparation of reports is required
- Motivated to build a culture of innovation with aspirations to develop products that will change the lives of people with serious diseases, their families and society
Other Relevant Information
- Candidate will be working in office and controlled laboratory environments.
- There is a risk of potential exposure to chemicals, viral vectors and gene editing reagents, and biohazards consistent with somatic cell therapy culture.
- Working in the laboratory requires mandatory use of personal protective equipment.
- Understanding and compliance to an aseptic environment as required
- Limited travel may be required (