Lesaffre Group Lexington , MA 02421
Posted 2 weeks ago
As part of the Recombia team, you will interact frequently with leadership and work collaboratively with other lab/bench scientists to implement strain engineering and analysis workflows, including the Recombia team located in Brisbane, CA. Salary and equity for this position will be commensurate with experience.
Ideal candidates will have:
A PhD in Metabolic engineering, Biochemistry, Bioengineering, Microbiology, Biology, or related fields and 0-4 years of relevant industry or postdoctoral experience or MS/BS with 7-10 years of industry experience
Strong background in chassis development and metabolic engineering of microorganisms, including Saccharomyces cerevisiae, Yarrowia lipolytica, Pichia pastoris, Rhodosporidium toruloides, and bacteria, as shown by a relevant publication or job experience.
Experience with the design and construction of microbial strains containing heterologous biosynthetic pathways from plants, bacteria, and fungi for the high-level production of target natural products
Experience in molecular biology (e.g. PCR, DNA purification, cloning, genome editing, DNA assembly, DNA sequencing) of yeast and bacteria, especially in the development and use of tools for rapid and effective strain engineering
Demonstrated skills to generate new hypotheses using existing data, scientific literature, or metabolic models
Effective communication skills and experience working within a complex team
Strong organizational, strategic planning skills, and excellent record keeping
A good record of maintaining safe laboratory practices and work environment
Skills to mentor and manage junior researchers
Desirable experience and skills:
Knowledge and ability to analyze multi-omic data for optimization of pathways, including using transcriptomic data to optimize pathways
Creating knockouts using both genomic and transcriptomic data, and analyzing targeted and untargeted metabolic data
Programming and data analysis skills (Python, R, AWS, etc)
Familiarity with Benchling environment and their Developer APIs
Ability to travel (France and/or California) at least two weeks per year
Job Type:
Full-time
Experience:
Metabolic engineering, microbial genetics, natural product pathways, non-saccharomyces yeast engineering, bacterial engineering
Education:
Doctorate, MSc
Location:
Greater Boston Area; Bedford, MA, 01730
Benefits:
Health, Dental, and Vision insurance
Paid time off
Short- and long- term disability insurance
Parental leave
401k
Lesaffre Group