Scientist, Discovery Chemistry

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist in Discovery Chemistry in San Diego, CA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us.

We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it.

Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Global Discovery Chemistry group is committed to the delivery of high-quality drug candidates working with all five Janssen Therapeutic Areas (TAs). This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, enzymology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding individual to join our team as Scientist, Discovery Chemistry.

We are seeking an entry-level PhD chemist with excellent organic synthesis expertise to advance small molecule drug discovery programs toward the clinic. In this laboratory-based position, the successful candidate will partner with both internal and external medicinal chemistry teams to generate innovative solutions to synthetic and medicinal chemistry challenges within the context of small molecule drug discovery projects.

They will maintain close interactions with computer-assisted design scientists, biologists, pharmacologists, and pharmaceutical development scientists. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.

This individual must also excel in communication and have strong interpersonal skills necessary to influence in a collaborative multidisciplinary environment.

Responsibilities of the Scientist include:

Key Responsibilities:

• Maintaining a high level of productivity in the laboratory setting.

• Developing and executing clear synthetic strategies towards complex molecules using state-of-the-art synthetic methodologies.

• Independently designing and synthesizing drug-like molecules utilizing medicinal chemistry knowledge and an understanding of ADME, pharmacokinetics, optimal physicochemical properties, and AI/ML predictive tools.

• Collaboratively supporting the advancement of compounds through in vitro and in vivo studies to identify development candidates.

• Collaboration with structure-based design groups to impact rational design of molecules.