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Scientist, Biophysical Characterization (Spr/Bli)

Expired Job

Alector South San Francisco , CA 94080

Posted 2 months ago

At Alector, our mission is to harness the power of the immune system to cure neurodegeneration and cancer. Our team integrates experts in key biotechnology disciplines and is solely focused on developing cures for some of the most challenging diseases facing our society. We are supported on this mission by leading investors including OrbiMed, Polaris Partners, Google Ventures, Deerfield Management, Foresite Capital, Federated Kaufmann Fund, and many others. Among our strategic backers and partners, we are aligned some of the most innovative pharma companies such as AbbVie, Merck, and Amgen.

Would you like to take part in creating novel therapies that really make a difference in patients' lives? Do you desire both autonomy and collaboration in tackling scientific challenges that interest you? Would you like to be part of a talented team where everyone has a voice?

Use your hard-earned scientific skills to help us achieve our mission of saving lives by curing neurodegenerative diseases.

As a Scientist for the protein engineering team, youll work closely with scientists in both Research and Development to advance Alector programs forward. You will help contribute to a variety of programs across out portfolio. You will apply your existing technical skills, learn new skills, and play a key role in development of the programs and help grow the company and guide its direction. As an early hire, youll be influential in championing and developing Alectors culture.

During the first year, you will:
  • Build new in-house capabilities for label-free analytics
  • Help select new analytical platforms to support high throughput screening of antibodies, including affinity, competition assays, epitope binning/mapping, etc
  • Screen and characterize antibodies for binding using biochemical and biophysical assays, including SPR/BLI, ELISA, FACS and other related techniques.
  • Support antibody discovery and engineering activities through your skills in molecular biology, high throughput protein production and purification, etc.
  • Explore new technologies, opportunities and automation to improve the antibody discovery and engineering workflow and process

At Alector, we believe that high-performing teams include people from a wide variety of backgrounds and experiences who can challenge each others assumptions with fresh perspectives and bring creative ideas to the table. We are committed to building an open, diverse, and inclusive environment for all employees. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, sexual orientation, age, marital status, veteran status, or disability status, or any other characteristics protected under applicable federal, state, or local laws.

Alector is a phenomenal place to learn and experiment. If you excel in a dynamic environment where everyone is committed to finding a cure, where youll drive growth, this is the role for you. There is no limit to how far you can go with us.


We'd love to hear from you if:

  • Your academic background includes a Bachelors, Master's or PhD Degree in biology, biochemistry, bioengineering, molecular biology or a related scientific field
  • You have a minimum of 5 years of lab experience in industry (if Bachelors), minimum 3 years industry experience if Masters, or minimum 1 year of industry experience if PhD.
  • You have the ability to work in a self-directed manner with minimal oversight in the lab to meet goals under project timelines
  • You are capable of setting up an in-house analytical capacity including selecting instruments, designing experiments and generally serving as Alector's guru for label-free protein analytics
  • You have extensive hands-on experience with SPR/BLI instruments including high throughput affinity determination and epitope binning/mapping techniques
  • You have direct experience in antibody discovery and engineering techniques such as RNA extraction, molecular biology, small scale protein production and purification, etc.
  • You take pride in being self-motivated, a fast learner, and creative problem solver
  • You have a point of view but are low ego


While weve focused on what to look forward to during the first year and beyond, Day One is great, too: committed colleagues, a bold and important company goal, state-of-the-art offices and labs in the heart of the biotech area, competitive compensation and benefits. But these matter only if youre excited to build and own something great, and tackle these challenges with us. Come join us.

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Scientist, Biophysical Characterization (Spr/Bli)

Expired Job