Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for a Scientist, located in Malvern, PA.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science.
We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.
The Biotherapeutics Development-Analytical Development (BTD-AD) discovers and develops creative large molecule solutions to address significant unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases.
The Analytical Development organization is continuing to build key scientific expertise in protein and vaccine characterization, and primary structure elucidation. Are you a hardworking scientist willing to bring your expertise to exciting efforts in novel areas of protein characterization?
You will join the Primary Structure team within the Characterization group in the BTD-AD department to conduct product characterization and process development activities. Your duties and responsibilities will include:
Operate state-of-the-art LC and MS instrumentation
Learn and utilize different software packages for LCMS/protein analysis
Perform LCMS-based quantitation of post-translational modifications
Design and execute peptide mapping / MS experiments on monoclonal antibodies and recombinant proteins to assess sequence coverage and sites of modification
Contribute to IND, IMPD, BLA, and other regulatory filings
Develop/optimize assays, write protocols, reports
Oversee testing to support analytical development, manufacturing process development, process validations, and manufacturing investigations
Lead or facilitate technical discussions and participate in cross-functional teams at project-related meetings
A Ph.D. in analytical chemistry, biochemistry or a related discipline with relevant experience OR an MS with at least 5 years of relevant experience is requried
Hands-on experience with LC-MS is required
Experience with MS characterization of proteins is preferred
Competency at developing, optimizing and trouble-shooting assays is required
Experience maintaining high quality documentation, analyzing and properly interpreting data, and preparing reports, SOPs or other technical reports is requried
A Deep understanding and experience in the application of various GXP concepts is preferred
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Janssen Research & Development, LLC. (6084)
Johnson & Johnson