Rtp-Research Fellow - Dr. Gupta Lab

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Responsibilities

A Post-doctoral Research Fellow position is being offered by the lab of Dr. Navin Gupta in the department of Biochemistry and Molecular Biology, and division of Nephrology and Hypertension, at Mayo Clinic - Rochester.

Research projects are related to disease modeling and therapeutic discovery using 3-dimensional spheroids of human stem cell-derived kidney tissue, termed kidney organoids. Actively funded projects include 1. Modeling diabetic nephropathy in vascularized kidney organoids-on-chip with emphasis on the role of intercellular NOTCH/DLL4 signaling as a driver of histologic changes, 2-3.

Modeling polycystic kidney disease with genotype-phenotype correlation, as a platform to conduct gene therapy via viral transfer, as well as to interrogate novel cystogenic pathways and identify druggable targets. This research is supported by the NIH - NIDDK, the Polycystic Kidney Disease Research Resource Consortium, the Mayo Clinic Center for Clinical and Translational Science (CCATS), and a Kathryn and Roger Penske Career Development Award in Endocrinology.

Qualifications

Attributes of a highly desired candidate include:

• A doctoral degree with a background in cell biology, molecular biology, or a similar field. MDs with extensive bench research experience will also be considered.

• Prior experience with human pluripotent stem cells is preferred - training can be provided

• Experience with basic molecular biology and biochemical techniques

• Desire to learn new skills and perform meticulous work

• Ability to communicate well both verbally and written

Exemption Status

Exempt

Compensation Detail

Education, experience and tenure may be considered along with internal equity when job offers are extended.

Benefits Eligible

Yes

Schedule

Full Time

Hours/Pay Period

80

International Assignment

No

Site Description

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As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.

Recruiter

Victoria Esteves