Researcher 1

About the Job

The Lesne lab in the Department of Neuroscience is seeking a Researcher 1 to join their team! Job duties are as follows:

Total effort for the section below (60%)

• Colony management of genetically modified mice (including models of Alzheimer's disease and related dementias).

• Performance of various husbandry techniques including breeding procedures, microchip implantation, animal identification, tissue collection (tail snips, brain microdissection and harvesting), cardiac perfusions, and database management.

• Coordinate with project managers (graduate students, undergraduate students and researchers) in developing and maintaining breeding plans for various experimental studies.

• Cognitive/behavioral testing of mice using the Barnes maze, Y maze or Restaurant Row maze. This also includes data analysis using AnyMaze and exported data files for secondary analyses in Excel, JMP for statistics and/or MatLab.

Total effort for the section below (10%)

• Performance of laboratory techniques involved in genotyping genetically modified mice (i.e. DNA extraction, and PCR)

• Performance of brain tissue sectioning using a vibratome.

• Assist with general lab maintenance as needed including preparation of solutions, preparing glassware, and autoclaving lab supplies.

Total effort for the section below (30%)

• Performance of biochemical assays (SDS-PAGE, CN-PAGE, western blotting, dot blotting) and cell culture techniques.

• Performance of immunohistological assays (immunofluorescent labeling of brain tissue sections) and confocal imaging techniques. This also includes data analysis using the Imaris software package.

Qualifications

All required qualifications must be documented on application materials

Required Qualifications:

• B.A./B.Sc. in Biological or Behavioral Sciences or a combination of related education and work experience to equal four years.

• Must be able to work with genetically modified mice including identification procedures, euthanizing animals, and general husbandry.

• Experience with molecular biological techniques (e.g., DNA extraction and qPCR) and biochemical assays (e.g. Western blot, immunohistochemistry, and immunoprecipitation).

• Knowledge of Microsoft Office, Google Suite and database management systems (Access or other).

• Self-motivated, ability to work independently and as a team by coordinating schedule and work assignments with other laboratory personnel. This position requires excellent attention to detail and communication skills.

Preferred Qualifications:

• Completed coursework in Neuroscience or Neurobiology.

• Experience with murine husbandry practices and/or mouse behavioral testing.

• Experience in research lab setting.

About the Department

The Department of Neuroscience is committed to providing excellence in research, education, and public service. The Department of Neuroscience is part of the University of Minnesota's Medical School.

The Mission of the Department of Neuroscience

• Conduct outstanding neuroscience research.

• Be an educational resource to the Medical School and the University by providing neuroscience education to undergraduate, medical, dental, graduate, and post-graduate students.

• Provide leadership and be a focal point for the strengthening of neuroscience across the University by enhancing research, educational, and funding opportunities.

• Intentionally improve inclusivity by valuing diverse perspectives and actively supporting historically marginalized researchers, students, and neuroscience community members.

• Provide a bridge for the transfer of advances in basic neuroscience into clinical practice with the goal of improving the health of the people of Minnesota.

• Enhance the understanding and appreciation of neuroscience by the people of Minnesota.

Benefits

Working at the University

At the University of Minnesota, you'll find a flexible work environment and supportive colleagues who are interested in lifelong learning. We prioritize work-life balance, allowing you to invest in the future of your career and in your life outside of work.

The University also offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off

• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program

• Low-cost medical, dental, and pharmacy plans

• Healthcare and dependent care flexible spending accounts

• University HSA contributions

• Disability and employer-paid life insurance

• Employee wellbeing program

• Excellent retirement plans with employer contribution

• Public Service Loan Forgiveness (PSLF) opportunity

• Financial counseling services

• Employee Assistance Program with eight sessions of counseling at no cost

Please visit the Office of Human Resources website for more information regarding benefits.

How To Apply

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will be given the opportunity to complete an online application for the position and attach a cover letter and resume.

Additional documents may be attached after application by accessing your "My Job Applications" page and uploading documents in the "My Cover Letters and Attachments" section.

To request an accommodation during the application process, please e-mail employ@umn.edu or call (612) 624-8647.

Diversity

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Employment Requirements

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

About the U of M

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by the Star Tribune as a Top Workplace for 2021, as well as by Forbes as Best Employers for Women and one of America's Best Employers (2015, 2018, 2019, 2023), Best Employer for Diversity (2019, 2020), Best Employer for New Grads (2018, 2019), and Best Employer by State (2019, 2022).