Research Technician

GENERAL SUMMARY/ OVERVIEW STATEMENT:

The Lindsay laboratory of the Cardiovascular Research Center in collaboration with the Musolino Laboratory at the Center for Genomic Medicine at Massachusetts General Hospital and Harvard Medical School, seeks an exceptional candidate for the position of research technician to implement studies involving cellular and animal models of rare cardiovascular diseases. The technician will receive support from current study staff, as well as guidance from the Principal Investigator(s). This position is ideal for a candidate looking for an entry position to a career in an academic science environment or translational research in biotech.

PRINCIPAL DUTIES AND RESPONSIBILITIES:

• Primary responsibility for management of knockout and transgenic mouse colonies

• Isolation of genomic DNA from tail biopsies

• Genotyping by PCR analysis

• Assisting with mouse anesthesia and surgery

• Immunohistochemistry

• Tissue culture

• Assisting with lab management

• Ordering of animals, chemicals, and supplies

• Coordination of equipment maintenance and repairs

• Design, plan, and execute cell-based, biochemical, and in vivo experiments necessary to validate target genes for therapeutic discovery.

• Contribute to scientific literature and present research at scientific forums.

• BS degree in life sciences (e.g., biology, biochemistry, or pre-med) required

• Previous research experience (2 years) involving small animal handling and surgery highly desirable

• Comfortable with computers and electronics

• Highly motivated

• Able to work independently as well as member of a team

• Excellent communication and interpersonal skills

• Attention to detail

• Accurate record keeping

• Additional specialized training: Neuroscience, Genetics, Molecular Biology, Stem Cell Biology, Blood Brain Barrier, Vascular Biology, Pre-Med preferred