Research Scientist, Immuno-Oncology Cell And Gene Therapy

About the Role

Location: Cambridge, MA

#LI-Onsite

We are dedicated to discovering innovative cancer therapeutics and therapeutic formats that transform patient lives and transform the field of cell therapy. We have an opportunity for a cell therapy scientist to join the Cell and Gene Therapy group within Oncology and contribute to developing pioneering CAR-T cell therapies. In this role, you will be a part of a dynamic, multidisciplinary discovery team interrogating unique cell therapy platforms and will generate data that increases our understanding of emerging CAR-T cell therapies. This will be a unique opportunity for you to combine your interest in immuno-biology of cancer, with your passion to discover and develop therapeutic approaches. Join us today and make a difference.

Your Key Responsibilities:

• Conduct detailed in vitro characterization and testing of cell therapy products using protein and gene expression analysis.

• Execute experiments, accurately record, analyze, and communicate data to senior staff and team members.

• Work with other team members to test, optimize and advance new cellular therapies into early development.

• Present results in team meetings and work collaboratively with other team members.

Diversity & Inclusion / EEO

We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:

• Novartis: e-mail [email protected] or call +1 (877)395-2339

• Sandoz: e-mail [email protected] or call: +1-609-422-4098

Role Requirements

Essential Requirements:

• BS/MS degree in Biology-related or Engineering subject area with 2+ years of relevant biomedical research experience. Job title level will commensurate with experience.

• Knowledge of immunology, cellular therapies, molecular biology and/or tumor immunology.

• Understanding of ex-vivo cell-characterization by multi-color FACS and cytokine profiling (ELISA/MSD/Luminex), and gene expression analysis (qPCR, RNAseq).

• Prior experience with immune cell isolation techniques and the culture of primary human T cells.

• Strong verbal and writing skills for documentation of data, and communication of progress to manager and other team members.

• Ability to work in a fast-paced and team-oriented environment and adapt to changing directions/priorities.

• Demonstrated ability to quickly learn and perform in new areas, implement new techniques and instrumentation.

• Scientifically self-motivated.

Desirable Requirements:

• Experience with engineered T cell manufacturing and culture, including process optimization and functional testing of engineered T cells.

• Familiarity with construct design and proficiency in related software.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining

to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Read our handbook to learn about all the ways we'll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

Commitment to Diversity & Inclusion: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $66,000 - $99,000/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together?