Vertex Pharmaceuticals Incorporated is offering an exciting opportunity for an exceptional Biologist to join our Exploratory Research team in Boston. We are seeking a highly motivated, independent scientist to identify novel pathways/targets to drive drug discovery research in genetically validated diseases. The scientist will also develop and implement novel assays and cellular models to interrogate these therapeutic targets. Vertex is a leader in specialty disease research, including cystic fibrosis, alpha 1 antitrypsin deficiency, sickle cell disease, genetic kidney disease, and others not yet publicly disclosed.
Utilize modern molecular biology techniques to validate novel targets in severe genetic diseases with a high unmet medical need
Develop in vitro biochemical and cell-based assays aimed at discovering novel therapeutics
Independently design, perform, and direct key studies to understand the mechanism of action at the molecular and cellular level, and support drug discovery projects
Critically analyze and interpret complex data, and effectively document and communicate results to a variety of audiences
Work effectively with colleagues from cross-functional disciplines (chemistry, pharmacology, DMPK and toxicology).
Collaborate and deliver on objectives successfully in a fast-paced, highly-matixed work environment
Ph.D. or (equivalent degree) in Cellular or Molecular Biology, Genetics, or Biochemistry and 0-5 years' post-doctoral experience in molecular biology, biochemistry and assay development
Skilled in molecular and cell biology techniques including, but not limited to, CRISPR/Cas9 gene editing, cloning, Western blotting, quantitative PCR, immunofluorescence techniques, or other techniques that would add value in new project identification and validation.
It is essential that the candidate possess strong communication and problem-solving skills, and have strong collaboration skills to be effective in a team environment focused on drug discovery
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.
Vertex Pharmaceuticals, Inc