Research Scientist, Discovery Biology

Cytokinetics, Incorporated South San Francisco , CA 94080

Posted 3 months ago

As a leader in muscle biology research, we are dedicated to our mission of improving the lives of people confronting Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and best-in-class muscle inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised and/or declining. As a leader in muscle biology and the mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to impact muscle function and contractility. We take a purpose-driven approach by leveraging our unique muscle biology expertise to engineer compounds with specific characteristics aimed at treating diseases that impact muscle function, like heart failure, hypertrophic cardiomyopathy, ALS and SMA.

We view our employees as the unequivocal ingredients to success. Each and every employee is an integral member of the Cytokinetics team, contributing to our shared goal of improving lives. While expectations of our employees are high, there is an equal commitment to ensuring that contributions are recognized and rewarded. We seek exceptional individuals to join us in our mission to develop potential medicines to improve the healthspan of people with cardiovascular and neuromuscular diseases of impaired muscle function.

We seek a highly motivated and accomplished Research Scientist to join Discovery Biology team.

Responsibilities:

  • The candidate will be involved in designing, optimizing, establishing and executing a wide-range of biochemical and cell-based assays to support our preclinical drug discovery efforts in the areas of skeletal muscle contractility and metabolism.

  • The candidate will play an integral role in championing new projects and ideas for discovery of novel therapeutics, conduct research both working independently, and in a team-based setting

  • As a key team member, the candidate will provide regular project updates and progress in team meetings, providing scientific and technical guidance to advance programs

Qualifications:

  • The position requires a PhD and Postdoctoral training in molecular and cell biology or related field with 0-3 years of experience in a biotechnology setting

  • Extensive knowledge and experience in the design, execution, and analysis of in vitro biochemical assays, as well as assays of myocyte function, metabolism, cell signaling (including Ca2+), and viability is required

  • Experience with quantitation and genetic manipulation of protein expression to create cellular models of human disease is required

  • Experience with energy metabolism and bioenergetics is preferred

  • Experience with cell culture, measurement of gene and protein expression, fluorescence microscopy, high content imaging and integration with image analysis software is preferred

  • Positive can-do attitude, strong organizational and time management skills, attention to detail, and flexibility are required

  • Enthusiasm for working in a team-based, multi-disciplinary environment, paired with excellent verbal and written communication skills, is required

Our passion is anchored in rigorous and diligent scientific and clinical approaches to the discovery and development of novel mechanism therapeutics. With gratitude for the commitments and convictions of our employees who are inspired by the courage of patients we aim to serve, we believe Cytokinetics will continue to be a pioneering, values-driven, sustainable, fully integrated biopharmaceutical company.

Please visit our website at: www.cytokinetics.com

Cytokinetics is an Equal Opportunity Employer


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Research Scientist, Discovery Biology

Cytokinetics, Incorporated