Research Associate/Senior Research Associate, Protein Engineering

SystImmune Inc. is a dynamic clinical-stage bio-pharmaceutical company headquartered in Redmond, WA. Our mission is to revolutionize cancer treatment by developing breakthrough-therapeutic multi-specific antibodies and ADCs. With eight assets in ongoing clinical trials and a robust preclinical pipeline, we are committed to advancing innovative therapies from discovery through clinical development.

Job Summary:

We are seeking a highly skilled and motivated Research Associate or Senior Research Associate to join our Protein Engineering Group. The successful candidate will play a critical role in advancing our protein engineering efforts through numerous techniques, including molecular biology, protein purification, Biolayer interferometry (BLI), and protein stability measurements. Ideal candidates will have a strong background and interest in the properties and functions of proteins and protein-protein interactions. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

Responsibilities:

• Protein Purification: Perform affinity chromatography, ion-exchange chromatography, and size-exclusion chromatography using FPLC systems.
• Protein Analytics: Conduct size-exclusion chromatography on HPLC systems to assess purity and stability.
• Mammalian Expression & Cell Culture: Transfect mammalian cells for protein expression and maintain cell lines.
• Molecular Biology: Utilize techniques such as Gibson Assembly, PCR, gel electrophoresis, DNA sequencing, and plasmid preparations.
• Data Analysis & Reporting: Analyze experimental data, generate reports, and present findings to cross-functional teams.
• Collaboration & Innovation: Work closely with multidisciplinary teams to contribute to project planning and execution.
• Lab Management: Maintain accurate records, ensure safety compliance, and support lab organization and operations.

Qualifications:

• Education: Bachelor's or Master's degree in biochemistry, molecular biology, structural biology, or a related field.
• 2+ years of laboratory experience, with at least 1+ year of industry experience in drug development preferred. 1+ years of hands-on experience in protein purification or molecular biology.
• Proficiency in protein purification and handling is required
• Experience with mammalian expression systems is strongly preferred.
• Strong background in molecular biology and biochemistry.
• Familiarity with data analysis software and statistical tools.
• Ability to maintain records within a laboratory information management system (LIMS).
• Excellent problem-solving and troubleshooting abilities.
• Strong organizational and time management skills.
• Ability to work independently and as part of a team.
• Effective verbal and written communication skills.

The hiring pay range for this position is $65,000 - $110,000 per year based on skills, education, and experience relevant to the role.

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery or IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. To be considered, please send your CV and cover letter to [email protected]