Seeking a highly motivated and enthusiastic Research Associate I/II who will be part of the Material Generation Team (MGT) with a focus on purification at Seattle Genetics, a leader in the development of innovative therapeutics like antibody drug-conjugates (ADCs) in the field of cancer. The candidate will join an exciting and dynamic team environment and assist in supporting all development programs in supplying critical material needed for cross functional development and IND enabling studies. In addition, the candidate will also support the evaluation of novel technologies and process/platform improvements.
RAI and RAII
Perform downstream purification operations to the final formulated mAb intermediate
Perform mammalian cell culture including initiation and propagation of cell lines using aseptic techniques
Prepare buffer and media solutions to support experiments in the lab
Maintain accurate and detailed records of all lab activities and work routinely with electronic data records and applications
Perform data analysis to support planning, execution and interpretation of experimental data
Perform bioreactor, Purification skid, and chromatography column maintenance
Execute assigned projects as part of a team and present key findings in a team setting regularly
Present results both within group and to cross-functional teams
RAII (all above plus)
May be representative for functional area on CMC teams
Demonstrates understanding of AKTA and UNICORN programming
RAI: Bachelor's Degree in Chemistry, Biochemistry, Bioengineering, Chemical Engineering or related field with some hands on lab experience.
mAb purification experience (filtration and chromatography)
Familiar with following detailed lab operating procedures and safety guidelines
Some familiarity with bioreactor operations and/or lab automation
Detail oriented, strong organization and time management skills
Team player, great communication and leadership skills
Motivated and willing to learn and grown
Creative problem solver willing to troubleshoot and establish new protocols
Experience using lab software and/or electronic lab notebooks
RAII: B.S. in above fields + 2yr's of experience or M.S. and 0 - 2 yr's experience
Prior experience working with protein purification
Prior experience working in an upstream cell culture environment
Proficient in troubleshooting and using lab automation
Prior experience data management using ELN
As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visitwww.seagen.com.
Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.