Sorry, this job is no longer accepting applications. See below for more jobs that match what you’re looking for!

Research Associate I/Ii, Pharmacology

Expired Job

Editas Medicine, Inc. Cambridge , MA 02138

Posted 3 months ago

Location- Cambridge, MA.

Editasis seeking a highly motivated Research Associate I/II to join our ex vivopharmacology group. The candidate will be responsible for conductingpreclinical animal studies to support the development of gene-editing based exvivo cell therapies in multiple disease areas, including sickle cell diseaseand beta-thalassemia. The successful candidate will be part of a dynamic teamand will interact with the discovery, platform, process development groups, aswell as contract research organizations. The successful candidate shoulddemonstrate strong work ethics and ability to work in a fast-paced and highlydemanding work environment.

KeyResponsibilities

  • Executein vivo studies including xenotransplantation of human hematopoietic stem andprogenitor cells in immunodeficient mice.

  • Performroutine injections (sc, ip, iv) in mice, monitor animal health, collect bloodsamples, perform necropsies.

  • Establishnew animal models as needed.

  • Cultureprimary cells and cell lines.

  • Performbasic molecular biology work such as DNA and RNA extraction and PCR.

See if you are a match!

See how well your resume matches up to this job - upload your resume now.

Find your dream job anywhere
with the LiveCareer app.
Download the
LiveCareer app and find
your dream job anywhere
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Senior Associate Scientist In Vivo Pharmacology & Toxicology

Bluebird Bio, Inc.

Posted 1 week ago

VIEW JOBS 11/6/2018 12:00:00 AM 2019-02-04T00:00 The Preclinical Development group works with bluebird bio's discovery platforms and translational research teams to generate the hypotheses, mechanism-of-action, and efficacy data that fuel the bluebird pipeline. We also work with our clinical and regulatory teams to generate the toxicology and biodistribution data that is critical to translating each of bluebird's innovative therapies safely from research into patients. In doing so, we continuously strive towards our mission to be the biotech world's best preclinical development organization for immunotherapy and gene therapy. Our valued associates experience room to grow their careers, a supportive, flexible and collaborative work environment, and respect for a diversity of experiences and perspectives. Responsibilities: * Design, plan and execute in vivo studies including xenogeneic mouse tumor models and murine stem cell engraftment models in collaboration with research scientists. * Perform routine injections (sc, ip, iv) in mice, monitor animal health, collect blood samples, measure tumors, perform necropsies and collect and record data. * Analyze data using software including Excel and GraphPad Prism; prepare and present data to various groups within the organization. * Establish new animal models as needed, including pilot studies for model development and troubleshooting. * Contribute to the initial and recurrent training of junior vivarium staff members. * Perform routine cell culture and maintain tumor cell lines used in xenograft models. Qualifications: * BA/BS or MS with 7-10 years' experience in the biotechnology or pharmaceutical industry * Experience with in vivo animal studies required, including animal handling, performing routine injections, necropsy, collection of blood and tissues * Expertise with murine intravenous injections * Perform in vitro assays in support of PK / PD studies including ELISA, ELISPOT, flow cytometric and qPCR analysis of blood, serum and tissue samples - preferred * Desire and drive to learn and understand the basic biologic mechanisms underpinning our immunotherapy and gene therapy products * Experience in maintaining a laboratory notebook and following written protocols * Familiarity with programs such as Excel, GraphPad Prism and PowerPoint for data entry, analysis and presentation * Team player with excellent oral and written communication skills and "do-what-it-takes" attitude * Independently motivated, detail-oriented and excellent problem-solving abilities * Excellent organizational skills towards multi-tasking in an extremely fast-paced environment with changing priorities * Comfortable with rapidly changing schedules and priorities * Be ready to embrace the principles of the bluebird bio culture: b colorful, b cooperative, and b yourself Bluebird Bio, Inc. Cambridge MA

Research Associate I/Ii, Pharmacology

Expired Job

Editas Medicine, Inc.