Research Associate III (Ngs & Genomics)

Cystic Fibrosis Foundation Lexington , MA 02421

Posted 2 months ago

The Cystic Fibrosis Foundation (CFF) and its employees embrace their commitment to its core values. These core values are the pillars on which CFF stand and will continue to sustain us as we move forward.

  • Keep sight of what really matters: Our decisions are based on what is best for people with cystic fibrosis and their families.

  • Aspire for excellence in all we do: We take pride in our work. We are committed to continuous learning and improvement.

  • Stronger together: We collaborate and work together so that we can learn more and achieve more.

  • Innovate with courage: We embrace challenges. We reach beyond boundaries in pursuit of our vision.

  • Care about our people: We deeply care about each other and all who support our shared mission. We listen with respect. We support one another.


The Research Associate III possesses a strong desire to grow scientifically and contribute to the CFF mission of finding a cure for CF. Duties include independently performing laboratory experiments using standard techniques and equipment. Perform calculations to complete research test results; collate data; and perform analysis of lab results for discussion with supervisor. Collaborate across project and program teams to help develop and support fit-for-purpose NGS solutions and assay technologies. Troubleshoots experiments and communicate results to the Genomics and Bioinformatics teams.


  • Hands on preparation of various NGS libraries methods including Genotype by Sequencing (GBS), DNAseq, ChIPseq, ATACseq, 10X Genomics SCseq, RNAseq, and Novel long read mRNA isoform.

  • Operation and maintenance of Illumina and Nanopore sequencing platforms.

  • Troubleshooting and Quality Control of NGS experiments in collaboration with manager and Genomics team members.

  • Weekly participation in joint Genomics and Bioinformatics team meetings for discussion of data and suggested next steps.


  • Bachelor of Science in Life Sciences or Related Field and minimum of four (4) years of R&D Laboratory Experience or Master's with a minimum of two (2) years' experience in biotech or pharmaceutical industry.

  • Experience with basic molecular biology techniques including DNA/RNA extraction, quantitation (ddPCR, qPCR, nanodrop, Qubit), library construction, quality control is required.

  • Familiarity with basic NGS data analysis approaches is a plus.

  • Excellent organizational and communication skills while self-motivated, detail oriented, and flexible.

  • Detail-oriented and capable of multi-tasking in a dynamic team.


  • Reports to the Senior Scientist, IV (Head of NGS and Genomics); no direct reports.


  • Commute to lab every workday - Must have access to reliable transportation.

  • Occasional weekend work in the lab.

  • Annual/Biannual travel to scientific or technology-focused meetings as necessary.

  • Sitting, bending, reaching, and walking.

  • Ability to lift heavy objects (not to exceed 30 lbs.) for set-up of lab equipment.

The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of essential functions, responsibilities, or requirements.

Total Rewards:

The Cystic Fibrosis Foundation is committed to offering competitive compensation (base pay and incentive), benefits, and professional development opportunities that maximize our ability to recruit, retain, reward, and motivate a highly-qualified and diverse workforce. Our comprehensive benefits package includes medical, dental, and vision coverage; generous time-off and leave policies; a holistic well-being program; health savings and flexible spending accounts; employer-provided life and disability insurance; retirement savings benefits; and a variety of work-life benefits to support employees and their family members.

The CF Foundation is an equal opportunity employer that is committed to being an employer of choice, not just a good place to work, but a great and inclusive place to work. We strive to recruit and maintain a diverse workforce. Qualified applicants will receive consideration for employment without regard to race, physical or mental disability, color, religious creed, ancestry, national origin, religion, age, sex, marital status, genetic information or testing, gender identity and expression, sexual orientation or status as a Vietnam-era or special disabled veteran or any characteristic protected by law.

Reasonable Accommodation Notice:

The CF Foundation is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or would like to request an accommodation due to a disability, please contact us at

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Research Associate III (Ngs & Genomics)

Cystic Fibrosis Foundation