Research Associate, Data Science

Aduro Biotech, Inc. Berkeley , CA 94705

Posted 6 months ago

Research Associate, Data Science - Personalized Medicine LOCATION: Berkeley, CA USA REPORTS TO: Associate Director, Personalized Medicine


Aduro is an immunotherapy company with multiple therapeutic approaches in clinical development. The Translational & Predictive Medicine department contributes to the development of investigational drugs by implementing strategies to bridge preclinical research with clinical development. The Personalized Medicine team within the Translational & Predictive Medicine department partners with other functional groups within Clinical Development for clinical study design and supports clinical trials with pharmacodynamic biomarker readouts, prognostic and predictive biomarkers as well as companion diagnostics, if required.

We are seeking a self-motivated and detail-oriented Research Associate with a B.S. or M.Sc. in Biology or Computational Biology to join a fast-paced team. This individual will independently implement and maintain a biospecimen monitoring suite and support biospecimen handling and processing including qualification of clinical site biospecimen processing capabilities. The candidate will also be responsible for developing and maintaining data collection and management systems that support cross-platform compilation and analyses of clinical and translational research data. The Research Associate may be involved in analysis of tumor immune microenvironment and immune mechanisms to provide support for the Personalized Medicine team to identify pharmacodynamic biomarkers as well as potential biomarkers of response and resistance to targeted therapies. This role requires independent critical thinking and organizational skills, excellent attention to detail with the ability to anticipate infrastructure risks/issues and pro-actively provide mitigation solutions. The candidate will contribute to key studies which will have a direct impact on the success of our therapeutic programs.


  • Implement and maintain biospecimen monitoring suite

  • Support biospecimen processing and handling and qualification of clinical site biospecimen capabilities

  • Develop, implement and maintain data collection and management systems and data analysis templates to improve data workflow

  • Develop and implement systems for data monitoring and data integrity, including documentation and validation of programming scripts

  • Support bioinformatics efforts in the Translational & Predictive Medicine department

  • Train colleagues on use of computational assets

  • Perform immune assays using human biological samples (serum, tissue, PBMC, urine) and support data analysis for immune monitoring of patients enrolled in Aduro-sponsored cancer immunotherapy clinical trials

  • Generate SOPs, validation plans and reports, and other related documents for review by senior staff while maintaining excellent lab notebook documentation practices

  • Evaluate new assay technologies and innovate novel assay/methodologies that could improve existing analytical methods

  • Work cross-functionally with other research teams and with other departments within the company to support product characterization at different stages of development


  • B.S or M.S. in Biology, Computational Biology, or a related field

  • 5-8 years relevant industry experience

  • Experience in a biotech environment is required, additional experience in a global pharma company is beneficial.

  • Proficiency in Microsoft Excel, GraphPad Prism required; working knowledge of FlowJo/FCS Express, online bioinformatics tools preferred

  • Working knowledge of programming languages such as SAS, Python, R, Perl preferred

  • Working knowledge of statistical software programs such as SPSS, JMP preferred

  • Experience working under SOPs, with understanding of GxP compliance preferred

  • Hands-on experience working with human biological samples including proficiency with PBMC isolation

  • Tissue culture experience of cell lines and primary cells is desired

  • Hands-on experience performing immunoassays (Luminex, ELLA, FACS, ELISA, ELISPOT)

  • Experience with drafting summary reports and protocols

  • Excellent verbal and written communication skills

  • Ability to work in a cross-functional, matrixed team environment and adapt quickly to changing priorities and responsibilities

  • Be an effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines

Aduro Biotech, Inc. is at the forefront of discovery, development and commercialization of breakthrough immunotherapies. We provide a workplace where employees excel, thrive and deliver value to patients, their families and our partners. Aduro's headquarter office is located in Berkeley, California with an international office in Oss, The Netherlands.

Aduro Biotech, Inc. offers a competitive salary and benefits package. We are an Equal Opportunity Employer.

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Research Associate, Data Science

Aduro Biotech, Inc.