Research Assistant II Lab

Basic Qualifications

College background and 1-2+ years of experience.

Additional Information

This is a two-year term position from the date of hire, with the possibility of extension, contingent upon work performance and continued funding to support the position.

Offer contingent upon successful completion of a pre-placement medical evaluation.

The health of our workforce is a priority for Harvard University. With that in mind, we strongly encourage all employees to be up-to-date on CDC-recommended vaccines.

Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.

The Harvard Medical School is not able to provide visa sponsorship for this position.

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Position Description

The Brugge lab has a long-standing interest in studying ovarian cancer using innovative techniques, with the ultimate goal to help improve treatment strategies for patients. We are looking for a highly motivated and intellectually curious research assistant to join our team. The research assistant will be working on projects that investigate the mechanisms involved in ovarian cancer therapy resistance. There are opportunities to learn standard and high-throughput, multi-plex immunofluorescence and advanced techniques involving ovarian tumor culture systems, primary patient samples, and drug response analyses. The research assistant will be directly supervised and mentored by a postdoctoral fellow. Former technicians in the lab have co-authored high-impact publications and successfully moved on to MD and/or PhD programs as well as industry positions.

Duties and Responsibilities:

• Perform immunofluorescence staining of ovarian cancers, microscopy, image analysis;

• Carry out multiplex cyclic immunofluorescence (CyCIF) and antibody validation;

• Carry out drug dose-response curves;

• Perform standard molecular biology techniques, e.g., cloning, gene expression and knockdown, qRT-PCR, western blots;

• Maintain accurate and detailed records;

• Contribute to general lab tasks.