Frontera Therapeutics is seeking a Principal/Senior Research Associate to join our Preclinical Development team. The successful candidate will be a creative scientist with demonstrated in-depth knowledge and experience in bioanalytical assay development. This individual will be responsible for the development and execution of bioanalytical methods to support our AAV-based gene therapy programs independently or with the guidance of senior scientist. S/he will be required to design and conduct various bioanalytical assays. S/he will perform data analysis and present the data to the project team. This person will also provide technical support in bioanalytical development for cross-functional project teams within Frontera.
Independently or with guidance, design, develop, troubleshoot, qualify and implement various bioanalytical assays and provide various bioanalytical assay support for all gene therapy programs.
Conduct routine sample testing to support gene therapy research and development
Participate in departmental and cross functional project teams
Author study reports, SOPs, and assay procedures
Maintain detailed and well-organized documentation with best industry practice
Effectively analyze, summarize and present the data to the project teams
Collaborate with internal cross-functional team members
A B.S or M.S. in Cell and/or Molecular Biology, Biochemistry, Pharmacology, Immunology or related disciplines, with a minimum 5-10 years of academia laboratory or industry experience working in a neuroscience, immunology, AAV gene therapy, or bioanalytical laboratory.
Extensive technical and hands-on experience in various bioanalytical assays in different biological matrices (rodent, NHP, human, etc.) for non-GLP/GLP studies
In-depth knowledge and hands-on experience in cell culture and cell-based assays, cell and tissue processing, ELISA, western blot, RT-qPCR, bDNA assay, ddPCR, MSD, and other various platforms
Ability to learn new techniques and perform multiple tasks simultaneously
Proven ability to work independently and to be a good team player in a hands-on laboratory setting
Self-motivated, have pro-active and positive can-do attitude
Attention to details, with strong scientific, organizational and documentation skills
Strong analytical and problem-solving skills
Being willing to work in a fast-paced start-up environment with demonstrated capacity to handle multiple tasks and demands
Experience in AAV gene therapy is a plus
Frontera Therapeutics is an Equal Opportunity Employers and takes pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Benefits: Comprehensive Coverage of Benefits are available.