Principal Scientist

Pfizer Pearl River , NY 10965

Posted 2 months ago

POSITION SUMMARY

The incumbent develops and performs the diverse purification/recovery operations required to optimize the production of vaccine candidates. These include, but not limit to: recovery and purification of the candidate antigen and analytical characterization.

Expertise in a broad scientific and engineering principles will be used to develop new techniques, to critically evaluate results and to develop the experimental approaches to solve problems. Careful documentation and presentation of work is required. Work is to be done in a compliant manner according to SOP guidelines.

RESPONSIBILITIES

1.Develop, optimize, and scale-up recovery/purification for the preparation of vaccine candidates up to pilot plant scale.

2.Independently execute techniques for the recovery/purification of vaccine candidates, and provide supervision on special projects.

3.Presents problems and proposed solutions in discussion with group members. Offers insights based on experience to group members to help solve problems.

4.Critically evaluate own and others results to determine if processes are optimal or if opportunities exist.

5.Lead or participate the technology transfer of developed process to the clinical manufacturing site, and provide the technical support as needed.

6.Present periodic status updates to the project leader or team. Prepare technical reports, as needed.

7.Fully document laboratory experiments in electronic notebooks in a timely and compliant manner.

8.Execute analyses to characterize products. Assist in developing new assays and adapt existing assays to new materials. Discuss analytical issues with team members to help advance objectives.

9.Continuously evaluate each process and technique to determine the robustness and scalability of the process. If an operation has shortcomings or can be improved, develop and demonstrate use improved process.



  1. May be required to work on non-standard hours.

BASIC QUALIFICATIONS

  • PhD degree in Biochemistry or Chemistry, or Biochemical or Chemical Engineering or related discipline, minimum 8 years related experience or a relevant MS degree with minimum of 15 years relevant experience.

  • Experience in recovery and purification processes and at least 5 years experience in the industrial process development environment.

  • Experience with process scale-up and protein, plasmid and/or polysaccharide.

PREFERRED QUALIFICATIONS

  • Ability to work independently and in a collaborative team environment

  • Good written and verbal communication capabilities.

#LI-PFE

Other Job Details:

  • Eligible for Employee Referral Bonus

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure.

Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development



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