Pall Corporation of Westborough is seeking a Principal Scientist, Downstream Process Development. Pall's Process Development Services group provides our customers with best in class, innovative solutions for their downstream processing needs.
You will be a subject matter expert (SME) on manufacturing downstream processes for gene therapy and biologic applications working with new game changing technologies as well as provide scientific leadership to a small team of purification scientists reporting to the PDS lab Senior Manager. We are a fun, dedicated, hardworking, science driven organization, if this sounds like you, apply today!
Mentoring, executing, developing, providing guidance and managing workloads for the associates and being part of the hands on purification team.
Lead planning and execution of experiments for Pall downstream process development services including, depth filtration, chromatography I, polish chromatography TFF testing, sterile filtration, AKTA systems, or other DSP automation systems
Prepare project reports, by combining all data from a specific project from multiple individuals and making recommendations to clients on the direction of the project
Close interaction with the customer, presenting rational behind the experiment plan and experimental results
Prepare detailed protocols for execution for practical work and batch manufacturing records for process transfer to GMP manufacturing
Assist the project manager with administrative functions preparation of report drafts, budget tracking, draft proposals, BoM
Plan and execute experiments for DSP, experience with process development and scale-up of DSP unit-operations
Troubleshoot customer data, look for efficiencies and recommend right products and equipment to achieve best results
Train and support DSP activities in Portsmouth, UK PDS Lab
Perform analytical assays, possibly including gels, ELISA, qPCR, SDS-Page
Analyze project results and summarize for discussion with team. Make recommendations for further optimization
Bachelors in biological science / chemical engineering & minimum of 7 years of experience in protein purification or MS in biology / chemical engineering & 5 years of experience in protein purification or a PhD with 3 industrial relevant purification experience
Experience with purification with chromatography strength of viral particles (gene therapy and/or vaccine fields) or Monoclonal antibodies
Small scale purification development as well as large scale experience
A good understanding of product purification mechanisms
Prior experience compiling information into technical reports
Supervisory experience including performance management and development of employees
Ability to travel as needed.
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