Principal Scientist-Antibody Discovery

Working with Us

Challenging. Meaningful. Life-changing.

Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department.

From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Discovery Biotherapeutics team at BMS seeks to understand the structure and function of complex molecules such as bispecific antibodies, antibody drug conjugates and endogenous proteins in order to optimize their utility as therapeutic agents. We collaborate with biology and translational scientists imbedded in the Thematic Research Centers in order to prosecute Targets and Biological pathways with disease modifying potential. By using a blend of internal and external technologies and capabilities, we work to discover and deliver first-in-class as well as best-in-class molecules that warrant clinical evaluation for patient benefit.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

As part of the Discovery Biotherapeutics efforts at BMS, the Functional Assays team plays a key role in discovering and characterizing a first- and best- in-class Biotherapeutics pipeline. The Principal Scientist position is located in San Diego (CA), working with a cross-functional and matrixed teams across two other BMS sites located in Cambridge (MA) and the San Francisco Bay Area (CA). The successful candidate is expected to provide scientific and technical leadership from primary binder screen workflow design and execution to functional characterization of a wide range of biotherapeutic drug candidates, including antibody drug conjugates, bispecific and multi-specific antibodies, and other biomolecule formats to progress BMS's robust pipeline.

Expertise in antibody and protein structure-function screening is highly desired. A track record in automation or high-throughput screening assay development, antibody function, immunological and effector activity screening will be highly valued. A track record of demonstrating creativity, taking initiative and ability in influencing at all levels is desired.

The candidate should be able to thrive in a highly dynamic, supportive, yet independently thinking culture. Also, expectations of being pragmatic, comfortable with complex science and procedures, as well as practical and operationally experienced.

Responsibilities

• The successful candidate must be capable of working and operating in a laboratory environment for most of their work schedule.

• Manage multiple antibody/binder discovery processes - develop fit-for-purpose primary screening assay and provide characterization support for lead molecules.

• Position high-throughput, semi-automated or automated systems to enable rapid cellular functional screening of complex antibody candidates.

• Enable and maintain our biologics drug discovery operations: represent departmental function on project teams. Identify and manage research collaborations/CROs, collaborate with other stakeholders across Discovery Biotherapeutics sites.

Basic Qualifications

Bachelor's Degree with 8+ years of academic or industry experience

Or

Master's Degree with 6+ years of academic or industry experience

Or

PhD with 4+ years of academic or industry experience

Preferred Qualifications

• PhD with 4+ years of industry experience

• Significant experience in assay validation, antibody primary screening, and downstream MOA profiling

• In-depth knowledge and hands-on experience in various techniques for protein and antibody characterization, including BLI or SPR, flow cytometry, and high content imaging

• Data processing experience with workflows using Genedata or other equivalent data management system

• Hands-on experience working with neurodegenerative, immunosciences, or oncology biologics

For California Sites - The starting compensation for this job is a range from $121,000 - $167,200, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience.

For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as "Transforming patients' lives through science ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility.

For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer.

If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.