Sorry, this job is no longer accepting applications. See below for more jobs that match what you’re looking for!

Postdoctoral Researcher, Functional Genomics Of Autophagy

Expired Job

The Broad Institute Cambridge , MA 02138

Posted 5 months ago

Job Description:

Job Description

The Xavier Lab in the Infectious Diseases and Microbiome program of The Broad Institute of MIT/Harvard is looking to hire a Postdoctoral Associate with a strong background in the functional genomics of autophagy. The laboratory of Dr. Ramnik Xavier (Core Member of the Broad Institute and Director of the Center for Computational and Integrative Biology at Massachusetts General Hospital) leverages clinical data from one of the world's leading hospitals and large scale chemical biology and genetics experiments performed at the Broad.

Recently, the lab has discovered how polymorphisms in genes such as GPR65, C1orf106, and CARD9 can influence development and progression of disease by affecting processes including lysosome function, intestinal barrier integrity, and innate/adaptive immunity. Autophagy is altered in several diseases and elucidating its regulatory mechanisms will advance our understanding how cells defend against pathogens and potentially identify new therapeutic modalities.

DUTIES

Postdoctoral researchers closely interact with a dynamic team of Broad Institute scientists and to pursue fundamental research questions, with an emphasis on novel discoveries that will result in high impact publications. This position focuses on developing new a approaches to study how the autophagy pathway maintains cellular homeostasis by regulating lysosomal degradation of misfolded proteins, damaged mitochondria, and intracellular pathogens.

QUALIFICATIONS

  • Excellent experimental and organization skills

  • Ph.D. or M.D./Ph.D. in immunology, cell biology or molecular biology. Areas of focus include: mechanisms of selective autophagy, role of autophagy in immune disorders, mouse models, and CRISPR-based functional screening

  • Strong publication record

  • Familiarity with functional genetic and/or genomic data is preferred

  • Ability to communicate scientific material and work well in a collaborative environment

EOE / Minorities / Females / Protected Veterans / Disabilities

EEO is The Law - click here for more information

Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled


upload resume icon
See if you are a match!

See how well your resume matches up to this job - upload your resume now.

Find your dream job anywhere
with the LiveCareer app.
Mobile App Icon
Download the
LiveCareer app and find
your dream job anywhere
App Store Icon Google Play Icon
lc_ad

Boost your job search productivity with our
free Chrome Extension!

lc_apply_tool GET EXTENSION

Similar Jobs

Want to see jobs matched to your resume? Upload One Now! Remove
Postdoctoral Researcher Optimization And Inference

Mitsubishi Electric Research Labs

Posted Yesterday

VIEW JOBS 1/17/2019 12:00:00 AM 2019-04-17T00:00 <h3></h3>AL03: Algorithms / Postdoctoral Researcher - Optimization and InferenceMERLseeks a highly motivated individual to collaborate in one or more research projects on the optimization of discrete network flows in problems relating to transport and inference. Some of the application areas we are currently studying include exotic people-moving systems, wireless communications, image denoising and enhancement, and medical image interpretation. Duties will include original research, algorithm development, software implementation, and extensive simulation, testing, and analysis. The candidate may also elect to devote part of each week to independent research.<p><br></p><p>Research Area: <a href="https://workable.com/nr?l=http%3A%2F%2Fwww.merl.com%2Fresearch%2FAlgorithms" rel="nofollow noreferrer noopener" class="external">Algorithms</a></p><p><a href="https://workable.com/nr?l=http%3A%2F%2Fkross.merl.com%2Fresearch%2Fdata-analytics" rel="nofollow noreferrer noopener" class="external"></a>Contact: <a href="https://workable.com/nr?l=http%3A%2F%2Fwww.merl.com%2Fpeople%2Fbrand" rel="nofollow noreferrer noopener" class="external">Matthew Brand</a></p><p><br></p><p>Mitsubishi Electric Research Labs, Inc. "MERL" provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, MERL complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.</p><p>MERL expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. Improper interference with the ability of MERL’s employees to perform their job duties may result in discipline up to and including discharge.</p><p><a href="https://workable.com/nr?l=http%3A%2F%2Fwww.merl.com%2Fpeople%2Fthornton" rel="nofollow noreferrer noopener" class="external"></a></p><p><strong>Requirements</strong></p><p><br></p><ul> <li>A Ph.D. in computer science or allied fields from a well-recognized institution (or equivalent training and experience); MERL will also consider exceptional candidates regardless of credentials.</li> <li>A balance of theoretical and practical orientation.</li> <li>Software prototyping and development skills.</li> <li>Background in probability, statistics, and discrete/continuous/convex optimization. Knowledge of computer vision, audition, and/or graphics a plus.</li> <li>The proven ability to make and publish fundamental innovations.</li> <li>Some relevant industrial experience.</li> </ul><p>This is a ground floor opportunity in a world-class research laboratory</p> Mitsubishi Electric Research Labs Cambridge MA

Postdoctoral Researcher, Functional Genomics Of Autophagy

Expired Job

The Broad Institute