Postdoctoral Fellow - Cell Therapy, Genomic Safety

Johnson & Johnson is currently seeking a Postdoctoral Fellow - Cell Therapy, Genomic Safety Discovery to join our Johnson & Johnson Innovative Medicine (J&J IM) Team located in Spring House, PA.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/ .

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

Johnson & Johnson Innovative Medicine (J&J IM) develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, cardiovascular and metabolic disorders, immunology, pulmonary hypertension, neuroscience, and infectious disease.

Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about J&J Innovative Medicine, visit https:// https://www.jnj.com/innovative-medicine .

The J&J IM Discovery, Product Development, & Supply (DPDS) Postdoctoral Fellowship Program helps early career scientists gain the training and experience needed to further their careers while addressing the needs of global healthcare. Postdocs work side-by-side with DPDS scientists on innovative research projects and have the opportunity to present and publish their work. They also learn the functional role of scientists in the pharmaceutical industry and receive valuable career advice from mentors while building a network of professional contacts and developing the skills needed to advance their careers.

The Preclinical Sciences & Translational safety (PSTS) group in collaboration with Cell Therapy group in Therapeutics Discovery (TD) seeks a motivated post-doctoral candidate to develop a novel assay to assess genomic safety of nuclease mediated gene editing. The post-doctoral candidate will work in close collaboration with PSTS, TD, and protein engineering group to develop a novel technique to measure off-target effects of genome editing tool in the induced pluripotent stem cells.

The qualified candidate is expected to have basic knowledge of cell culture, extensive knowledge of molecular biology techniques, and protein engineering. Join our team in bringing innovative and safe drug products for the patients in need.

The anticipated start date for this role is October 14th, 2024.

Key Responsibilities:

• Collaborate with various functions within Johnson & Johnson such as cell therapy, protein engineering, and genetic safety.

• Culturing and maintaining induced pluripotent stem cells.

• Perform cloning, expressions, purification of proteins and assess functional characteristics.

• Use molecular biology techniques such as DNA/RNA isolation and next generation sequencing to assess the function of proteins.

• Partner with bioinformatics team to perform analysis and interpretation of the results.

• Adhere to good laboratory practices.