Postdoctoral Fellow - Cell Therapy

Johnson & Johnson is recruiting for a Postdoctoral Fellow- Cell Therapy in the Johnson & Johnson Innovative Medicine (J&J IM) group located in West Chester, PA

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

For more than 130 years, diversity, equity & inclusion (DEI) has been a part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Rooted in Our Credo, the values of DEI fuel our pursuit to create a healthier, more equitable world. Our diverse workforce and culture of belonging accelerate innovation to solve the world's most pressing healthcare challenges.

We know that the success of our business - and our ability to deliver meaningful solutions - depends on how well we understand and meet the diverse needs of the communities we serve. Which is why we foster a culture of inclusion and belonging where all perspectives, abilities and experiences are valued and our people can reach their potential.

At Johnson & Johnson, we all belong.

Johnson & Johnson Innovative Medicine (J&J IM) develops treatments that improve the health of people worldwide. Research and development areas encompass oncology, cardiovascular and metabolic disorders, immunology, pulmonary hypertension, neuroscience, and infectious disease.

Our goal is to help people live longer, healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners and from clinics to hospitals. To learn more about J&J Innovative Medicine, visit https:// https://www.jnj.com/innovative-medicine.

The J&J IM Discovery, Product Development, & Supply (DPDS) Postdoctoral Fellowship Program helps early career scientists gain the training and experience needed to further their careers while addressing the needs of global healthcare. Postdocs work side-by-side with DPDS scientists on innovative research projects and have the opportunity to present and publish their work. They also learn the functional role of scientists in the pharmaceutical industry and receive valuable career advice from mentors while building a network of professional contacts and developing the skills needed to advance their careers.

The Cell Therapy group of Janssen Therapeutics Discovery seeks an enthusiastic postdoctoral fellow to join the Cell Therapy Gene Editing team, which investigates and implements genetic engineering strategies to enhance the activity of CAR T cells. Your project will use combinatorial pooled screening approaches to discover mechanisms controlling T cell fitness.

Success in this project will be enabled by strong molecular and cell biology skills, along with the ability to collaborate well with internal experts in T cell biology, functional genomics, and bioinformatics. Start the next phase of your career with us and contribute towards developing best-in-class cell therapies!

The anticipated start date for this role is October 14th, 2024.

Key Responsibilities:

• Isolating, culturing, and engineering, primary human T cells

• Evaluating T cell fitness through flow cytometry, scRNA-seq, and other methods

• Using a variety of molecular engineering approaches (viral transduction, CRISPR, etc) to screen for functional biology

• Collaborating with internal colleagues to successfully meet project goals