Postdoctoral Associate

Postdoctoral Associate

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Work type: Research Faculty

Senior management: Vice President for Research

Department: Fralin Biomedical Res. Institute

Location: Roanoke, Virginia

Categories: Research / Scientific

Job Description

The mission of our team is to translate novel drug-delivery technologies to treat children with brain tumors. The brain has a natural barrier that prevents toxins and other agents from reaching the brain.

This same barrier also limits the access of systemic treatments, including chemotherapy, targeted therapy, and immunotherapy, from reaching the tumor. We are interested in exploring the usage of focused ultrasound (FUS) and convection-enhanced delivery (CED). Using targeted ultrasound, or FUS, with microbubbles, the blood-brain barrier (BBB) can temporarily and reversibly open to allow for enhanced drug delivery to fight brain tumors. In addition, we are also exploring the use of direct catheter delivery of drugs to brain tumors using CED.

We are focusing on identifying novel methods to treat Pediatric Brain tumors using new Drug Delivery Approaches and novel agents. Our goal is to translate into Novel Clinical Trials for children suffering from brain tumors.

We are seeking candidates with experience in cell culture work, molecular biology, and preclinical tumor models. Successful candidates will be highly motivated individuals with a doctoral degree in Neurology, Oncology, or Immunology, have excellent communication skills, be able to function independently, and participate as part of a dynamic team. The successful candidate will be involved in generating preclinical data that will lead to the design a number of novel clinical studies in children with high-grade gliomas and other brain tumors.

Work Location:

Fralin Biomedical Research Institute at VTC, Roanoke, VA

https://fbri.vtc.vt.edu/

Documents Needed to Apply:

Curriculum Vitae

Cover Letter

List of References

If interested or have any questions regarding this position, please email hw2711@cumc.columbia.edu.

Required Qualifications

PhD in Oncology, Neuroscience, Immunology, or appropriate related disciplines. PhD must be awarded no more than four years prior to the effective date of appointment with a minimum of one year eligibility remaining.

Creative, independent, and highly motivated, with good communication skills.

Demonstrated publication of research findings in peer-reviewed journals.

Experience in cell biology, molecular biology, and preclinical animal models.

Preferred Qualifications

Experience with flow cytometry.

Experience with RNA sequencing and analysis.

Experience with gene-editing techniques in cells or animals.

Appointment Type

Restricted

Salary Information

Commensurate with experience

Review Date

4/26/2024

Additional Information

The successful candidate will be required to have a criminal conviction check.

About Virginia Tech

Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity.

The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College. The university has a significant presence across Virginia, including the Innovation Campus in Northern Virginia; the Health Sciences and Technology Campus in Roanoke; sites in Newport News and Richmond; and numerous Extension offices and research centers. A leading global research institution, Virginia Tech conducts more than $500 million in research annually.

Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law.

If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at sheltb@vt.edu during regular business hours at least 10 business days prior to the event.

Advertised: April 3, 2024

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